Other Financial Information - Schedule of Property and Equipment, Leasehold Improvements, and Related Accumulated Depreciation and Amortization (Detail) - USD ($) $ in Thousands	Mar. 31, 2016	Dec. 31, 2015
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 11,927	$ 11,869
Less: accumulated depreciation and amortization	(8,499)	(8,060)
Property and equipment, net	3,428	3,809
Manufacturing and Laboratory Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	7,060	7,040
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	4,441	4,441
Office Furniture and Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	113	135
Computer Equipment and Software [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	113	129
Construction in Progress [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 200	$ 124