Other Financial Information - Schedule of Property and Equipment, Leasehold Improvements, and Related Accumulated Depreciation and Amortization (Detail) - USD ($) $ in Thousands	Dec. 31, 2015	Dec. 31, 2014
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 11,869	$ 9,846
Less: accumulated depreciation and amortization	(8,060)	(6,778)
Property and equipment, net	3,809	3,068
Manufacturing and Laboratory Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	7,040	5,292
Office Furniture and Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	135	113
Computer Equipment and Software [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	129	152
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	4,441	3,367
Construction in Progress [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 124	$ 922