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Stock-Based Compensation Plans (Tables)
9 Months Ended
Sep. 30, 2020
Share-based Payment Arrangement [Abstract]  
Summary of Stock Option Activity
The following table summarizes stock option activity since January 1, 2020 for the 2019 Plan:
OptionsWeighted-
Average
Exercise
Price
Weighted-
Average
Remaining
Contractual
Term (Years)
Aggregate
Intrinsic
Value
Outstanding as of January 1, 2020456,645 $12.57 
Granted597,068 $12.24 
Exercised— $— 
Forfeited or expired(83,891)$13.32 
Outstanding as of September 30, 2020969,822 $12.31 9.41$6,075,771 
Options vested and expected to vest as of September 30, 2020969,822 $12.31 9.41$6,075,771 
Options exercisable as of September 30, 2020167,515 $12.51 8.90$1,015,048 
The following table summarizes stock option activity since January 1, 2020 for the Plans assumed from Vital:
OptionsWeighted-
Average
Exercise
Price
Weighted-
Average
Remaining
Contractual
Term (Years)
Aggregate
Intrinsic
Value
Outstanding as of January 1, 202014,403 $306.01 
Granted— $— 
Exercised— $— 
Forfeited or expired(14,403)$306.01 
Outstanding as of September 30, 2020— $— 0$— 
Options vested and expected to vest as of September 30, 2020— $— 0$— 
Options exercisable as of September 30, 2020— $— 0$— 
Schedule of Valuation Assumptions Used The following are the underlying assumptions used in the Black-Scholes option pricing model to determine the fair value of stock options granted to employees and to non-employees under this stock plan:
Nine Months
Ended September 30,
2020
Risk-free interest rate0.43%
Expected dividend yield0%
Expected volatility87.1%
Expected term of options (years)5.93
Schedule of Stock-based Compensation Expense for Stock Awards Recognized
Total stock-based compensation expense for all stock awards recognized in the accompanying unaudited condensed consolidated statements of operations is as follows (in thousands):

 Three Months
Ended September 30,
Nine Months
Ended September 30,
 2020201920202019
Research and development$254 $57 $450 $1,727 
General and administrative453 142 979 6,503 
Total$707 $199 $1,429 $8,230