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Stock-Based Compensation Plans (Tables)
6 Months Ended
Jun. 30, 2020
Share-based Payment Arrangement [Abstract]  
Summary of Stock Option Activity
The following table summarizes stock option activity since January 1, 2020 for the 2019 Plan:
OptionsWeighted-
Average
Exercise
Price
Weighted-
Average
Remaining
Contractual
Term (Years)
Aggregate
Intrinsic
Value
Outstanding as of January 1, 2020456,645  $12.57  
Granted25,118  $8.30  
Exercised—  $—  
Forfeited or expired(61,918) $13.47  
Outstanding as of June 30, 2020419,845  $12.19  8.75$411,847  
Options vested and expected to vest as of June 30, 2020419,845  $12.19  8.75$411,847  
Options exercisable as of June 30, 2020101,845  $12.61  7.35$72,388  
The following table summarizes stock option activity since January 1, 2020 for the Plans assumed from Vital:
OptionsWeighted-
Average
Exercise
Price
Weighted-
Average
Remaining
Contractual
Term (Years)
Aggregate
Intrinsic
Value
Outstanding as of January 1, 202014,403  $306.01  
Granted—  $—  
Exercised—  $—  
Forfeited or expired—  $—  
Outstanding as of June 30, 202014,403  $306.01  2.09$—  
Options vested and expected to vest as of June 30, 202014,403  $306.01  2.09$—  
Options exercisable as of June 30, 202014,403  $306.01  2.09$—  
Schedule of Valuation Assumptions Used The following are the underlying assumptions used in the Black-Scholes option pricing model to determine the fair value of stock options granted to employees and to non-employees under this stock plan:
Six Months
Ended June 30,
2020
Risk-free interest rate1.06%
Expected dividend yield0%
Expected volatility84.4%
Expected term of options (years)5.76
Schedule of Stock-based Compensation Expense for Stock Awards Recognized
Total stock-based compensation expense for all stock awards recognized in the accompanying unaudited condensed consolidated statements of operations is as follows (in thousands):

 Three Months
Ended June 30,
Six Months
Ended June 30,
 2020201920202019
Research and development$99  $1,670  $196  $1,670  
General and administrative270  6,361  526  6,361  
Total$369  $8,031  $722  $8,031