Other Financial Information

12 Months Ended

Dec. 31, 2017

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Other Financial Information

Other Financial Information

Property and Equipment

Property and equipment, leasehold improvements, and related accumulated depreciation and amortization were as follows (in thousands):

	December 31,
	2017			2016
Manufacturing, clinical and laboratory equipment	$	7,500		$	7,325
Leasehold improvements	4,727			4,450
Office furniture and equipment	234			220
Construction in progress	17			111
	12,478			12,106
Less: accumulated depreciation and amortization	(10,323		)	(9,601		)
Total	$	2,155		$	2,505

Depreciation and amortization expense was $998,000, $1.8 million and $1.3 million for the years ended December 31, 2017, 2016 and 2015, respectively.

Accrued Expenses

Accrued expenses consist of (in thousands):

	December 31,
	2017		2016
Accrued clinical and related costs	$	5,377	$	2,316
Accrued compensation and related taxes	3,591		2,154
Accrued other	173		186
Total	$	9,141	$	4,656