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Significant Agreements - Celgene, Accounting Analysis (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Significant Agreements    
Revenue from contract with customer $ 4,344 $ 2,780
Luspatercept | Collaboration, License, and Option Agreement    
Significant Agreements    
Payments received 186,200  
Sotarcept | Collaboration, License, and Option Agreement    
Significant Agreements    
Payments received 44,800  
Cost-sharing, net    
Significant Agreements    
Revenue from contract with customer 2,824 2,780
Cost-sharing, net | Collaboration, License, and Option Agreement    
Significant Agreements    
Revenue from contract with customer 4,300 $ 2,800
Regulatory Milestone | Luspatercept | Collaboration, License, and Option Agreement    
Significant Agreements    
Collaborative arrangement potential milestone payments on acceptance of regulatory application $ 25,000