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Net Loss Per Share (Details) - shares
shares in Thousands
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Net Income (Loss) Per Share    
Anti-dilutive common stock equivalents excluded from the calculation of diluted net loss per share (in shares) 4,841 4,797
Outstanding stock options    
Net Income (Loss) Per Share    
Anti-dilutive common stock equivalents excluded from the calculation of diluted net loss per share (in shares) 4,232 4,115
Common stock warrants    
Net Income (Loss) Per Share    
Anti-dilutive common stock equivalents excluded from the calculation of diluted net loss per share (in shares) 39 39
Shares issuable under employee stock purchase plan    
Net Income (Loss) Per Share    
Anti-dilutive common stock equivalents excluded from the calculation of diluted net loss per share (in shares) 13 13
Outstanding restricted stock units    
Net Income (Loss) Per Share    
Anti-dilutive common stock equivalents excluded from the calculation of diluted net loss per share (in shares) 557 630