The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
2U, Inc. COM 90214J101 64,893 1,005,930 SH   SOLE   544,580 0 461,350
AbbVie Inc. COM 00287Y109 315 3,262 SH   SOLE   3,262 0 0
Activision Blizzard, Inc. COM 00507V109 28,722 453,600 SH   SOLE   228,705 0 224,895
Adobe Systems Incorporated COM 00724F101 46,151 263,360 SH   SOLE   105,499 0 157,861
Alibaba Group Holding Limited COM 01609W102 54,414 315,572 SH   SOLE   166,822 0 148,750
Alphabet Inc. Class A COM 02079K305 36,281 34,442 SH   SOLE   18,178 0 16,264
Alphabet Inc. Class C COM 02079K107 1,208 1,154 SH   SOLE   1,014 0 140
Amazon.com, Inc. COM 023135106 172,539 147,536 SH   SOLE   76,051 0 71,485
Amgen Inc. COM 031162100 485 2,790 SH   SOLE   2,765 0 25
Amphenol Corporation COM 032095101 727 8,285 SH   SOLE   7,685 0 600
Apple Inc. COM 037833100 3,321 19,627 SH   SOLE   12,550 0 7,077
BEST Inc. COM 08653C106 21,486 2,392,645 SH   SOLE   1,333,945 0 1,058,700
Becton, Dickinson and Company COM 075887109 1,930 9,015 SH   SOLE   4,190 0 4,825
BioMarin Pharmaceutical Inc. COM 09061G101 23,622 264,905 SH   SOLE   107,155 0 157,750
BlackRock, Inc. COM 09247X101 1,154 2,247 SH   SOLE   2,197 0 50
Boeing Company COM 097023105 982 3,330 SH   SOLE   3,330 0 0
CASHMERE VALLEY BANK COM 14756K102 290 5,000 SH   SOLE   0 0 5,000
Carlisle Companies Incorporate COM 142339100 364 3,205 SH   SOLE   3,205 0 0
Celgene Corporation COM 151020104 68,074 652,295 SH   SOLE   308,720 0 343,575
Charles Schwab Corporation COM 808513105 98,485 1,917,166 SH   SOLE   915,850 0 1,001,316
CoStar Group, Inc. COM 22160N109 23,429 78,899 SH   SOLE   38,474 0 40,425
Comcast Corporation COM 20030N101 549 13,705 SH   SOLE   13,305 0 400
Constellation Brands, Inc. COM 21036P108 2,025 8,859 SH   SOLE   4,140 0 4,719
Costco Wholesale Corporation COM 22160K105 523 2,810 SH   SOLE   2,810 0 0
Ctrip.com International, Ltd. COM 22943F100 495 11,223 SH   SOLE   11,223 0 0
CyrusOne Inc. COM 23283R100 589 9,890 SH   SOLE   9,690 0 200
Despegar.com, Corp. COM G27358103 1,134 41,250 SH   SOLE   41,250 0 0
Ecolab Inc. COM 278865100 569 4,240 SH   SOLE   4,140 0 100
Exact Sciences Corporation COM 30063P105 98,856 1,881,545 SH   SOLE   920,915 0 960,630
Facebook, Inc. COM 30303M102 133,917 758,906 SH   SOLE   375,910 0 382,996
FedEx Corporation COM 31428X106 719 2,880 SH   SOLE   2,855 0 25
First Republic Bank COM 33616C100 41,261 476,234 SH   SOLE   223,286 0 252,948
Inphi Corporation COM 45772F107 35,028 957,050 SH   SOLE   471,725 0 485,325
International Flavors & Fragra COM 459506101 745 4,885 SH   SOLE   4,885 0 0
Intuit Inc. COM 461202103 1,862 11,804 SH   SOLE   3,375 0 8,429
JD.com, Inc. COM 47215P106 2,906 70,150 SH   SOLE   69,450 0 700
JPMorgan Chase & Co. COM 46625H100 1,803 16,860 SH   SOLE   16,560 0 300
Johnson & Johnson COM 478160104 1,287 9,210 SH   SOLE   9,035 0 175
Medidata Solutions, Inc. COM 58471A105 26,735 421,894 SH   SOLE   183,439 0 238,455
MercadoLibre, Inc. COM 58733R102 114,478 363,814 SH   SOLE   191,619 0 172,195
Microsoft Corporation COM 594918104 1,874 21,910 SH   SOLE   21,910 0 0
Monolithic Power Systems, Inc. COM 609839105 69,726 620,560 SH   SOLE   313,070 0 307,490
NVIDIA Corporation COM 67066G104 75,099 388,110 SH   SOLE   200,032 0 188,078
Netflix, Inc. COM 64110L106 159,100 828,819 SH   SOLE   420,166 0 408,653
Nevro Corp. COM 64157F103 43,863 635,330 SH   SOLE   304,800 0 330,530
Newell Brands Inc. COM 651229106 429 13,885 SH   SOLE   10,735 0 3,150
Noah Holdings Limited COM 65487X102 454 9,816 SH   SOLE   9,816 0 0
Okta, Inc. COM 679295105 406 15,868 SH   SOLE   15,868 0 0
PACCAR Inc COM 693718108 543 7,634 SH   SOLE   6,234 0 1,400
PayPal Holdings, Inc. COM 70450Y103 51,987 706,148 SH   SOLE   375,450 0 330,698
Paychex, Inc. COM 704326107 810 11,895 SH   SOLE   11,845 0 50
Portola Pharmaceuticals, Inc. COM 737010108 37,263 765,475 SH   SOLE   385,135 0 380,340
Priceline Group Inc. COM 741503403 2,197 1,264 SH   SOLE   117 0 1,147
Proofpoint, Inc. COM 743424103 51,560 580,560 SH   SOLE   301,520 0 279,040
QUALCOMM Incorporated COM 747525103 1,046 16,345 SH   SOLE   15,165 0 1,180
Redfin Corporation COM 75737F108 1,030 32,890 SH   SOLE   32,890 0 0
Regeneron Pharmaceuticals, Inc COM 75886F107 48,749 129,665 SH   SOLE   56,915 0 72,750
SPDR Trust Series 1 COM 78462F103 780 2,922 SH   SOLE   2,922 0 0
Schlumberger Limited COM 806857108 308 4,570 SH   SOLE   4,495 0 75
ServiceNow, Inc. COM 81762P102 55,065 422,310 SH   SOLE   207,964 0 214,346
Shake Shack Inc. COM 819047101 37,961 878,725 SH   SOLE   375,025 0 503,700
Shopify Inc. COM 82509L107 91,958 910,475 SH   SOLE   480,750 0 429,725
Snap Inc. COM 83304A106 976 66,800 SH   SOLE   66,800 0 0
Square, Inc. COM 852234103 3,616 104,300 SH   SOLE   104,300 0 0
Starbucks Corporation COM 855244109 1,357 23,624 SH   SOLE   22,824 0 800
Stitch Fix, Inc. COM 860897107 1,051 40,700 SH   SOLE   40,700 0 0
Teladoc, Inc. COM 87918A105 53,656 1,539,640 SH   SOLE   751,525 0 788,115
Tencent Holdings Limited COM 88032Q109 1,185 22,825 SH   SOLE   22,825 0 0
Tesla, Inc. COM 88160R101 112,470 361,234 SH   SOLE   181,709 0 179,525
The Estee Lauder Companies Inc COM 518439104 1,022 8,035 SH   SOLE   7,735 0 300
The Home Depot, Inc. COM 437076102 1,616 8,525 SH   SOLE   8,525 0 0
The Trade Desk, Inc. COM 88339J105 3,568 78,020 SH   SOLE   78,020 0 0
The Walt Disney Company COM 254687106 875 8,140 SH   SOLE   7,690 0 450
Ulta Beauty, Inc. COM 90384S303 27,979 125,095 SH   SOLE   51,295 0 73,800
Visa Inc. COM 92826C839 9,127 80,045 SH   SOLE   64,422 0 15,623
Walgreens Boots Alliance, Inc. COM 931427108 267 3,675 SH   SOLE   3,575 0 100
Wayfair Inc. COM 94419L101 50,137 624,605 SH   SOLE   328,285 0 296,320
XPO Logistics, Inc. COM 983793100 154,495 1,686,811 SH   SOLE   792,035 0 894,776
Zillow Group, Inc. Class A, Vo COM 98954M101 687 16,865 SH   SOLE   14,985 0 1,880
Zillow Group, Inc. Class C COM 98954M200 80,151 1,958,734 SH   SOLE   1,008,139 0 950,595
Zoetis Inc. COM 98978V103 1,769 24,550 SH   SOLE   9,765 0 14,785
lululemon athletica inc. COM 550021109 46,677 593,930 SH   SOLE   241,480 0 352,450