Exhibit 24.10

                                POWER OF ATTORNEY

KNOW ALL BY THESE PRESENTS:

The undersigned, Linda S. Grais, hereby constitutes and appoints Karen A. Wilson
as her true and lawful Attorney-in-Fact, with full power in her name and on her
behalf, to take all actions and do all things necessary with respect to all
matters arising in connection with the ownership reporting requirements of the
securities laws of the United States, including the execution and delivery of
all documents in connection therewith.

The undersigned agrees to indemnify said Attorney-in-Fact against, and hold her
free and harmless from, and all loss, cost, expense, damage or liability which
she may incur or sustain as a result of any action taken by her in good faith
pursuant to this Power of Attorney.

This Power of Attorney shall remain in full force and effect until revoked in
writing by the undersigned and the authority granted herein may be relied upon
by any person until such person has actually received written notice of
revocation.

IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 7th
day of November, 2007.

                                        LINDA S. GRAIS

                                        /s/ Linda S. Grais
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