The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ADAMS EXPRESS CO COM 006212104 3,137 219,530 SH   DFND 1 219,530 0 0
ADVENT CLAYMORE ENH GRW & IN COM 00765E104 1,418 162,100 SH   DFND 1 162,100 0 0
AETNA INC NEW COM 00817Y108 714 4,700 SH   DFND 1 4,700 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 17,260 141,859 SH   DFND 1 141,859 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 27,673 196,400 SH   DFND 1 196,400 0 0
ALIGN TECHNOLOGY INC COM 016255101 19,240 128,165 SH   DFND 1 128,165 0 0
ALLERGAN PLC SHS G0177J108 8,848 36,400 SH   DFND 1 36,400 0 0
ALPINE GLOBAL PREMIER PPTYS COM SBI 02083A103 1,032 162,732 SH   DFND 1 162,732 0 0
ALTICE USA INC COM 02156K103 6,063 187,700 SH   DFND 1 187,700 0 0
AMAZON COM INC COM 023135106 11,669 12,055 SH   DFND 1 12,055 0 0
AMERCO COM 023586100 26,763 73,110 SH   DFND 1 73,110 0 0
APPLE INC COM 037833100 68,355 474,620 SH   DFND 1 474,620 0 0
ARBOR RLTY TR INC COM 038923108 1,437 172,300 SH   DFND 1 172,300 0 0
ARES CAP CORP COM 04010L103 52,701 3,217,400 SH   DFND 1 3,217,400 0 0
ARES COML REAL ESTATE CORP COM 04013V108 4,571 349,200 SH   DFND 1 349,200 0 0
BAIDU INC SPON ADR REP A 056752108 14,036 78,474 SH   DFND 1 78,474 0 0
BANK AMER CORP COM 060505104 58,502 2,411,458 SH   DFND 1 2,411,458 0 0
BARINGS GLOBAL SHORT DURATIO COM 06760L100 453 22,900 SH   DFND 1 22,900 0 0
BIOGEN INC COM 09062X103 14,442 53,222 SH   DFND 1 53,222 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 4,554 50,145 SH   DFND 1 50,145 0 0
BIOVERATIV INC COM 09075E100 11,805 196,200 SH   DFND 1 196,200 0 0
BLACKROCK MUNI INTER DR FD I COM 09253X102 176 12,500 SH   DFND 1 12,500 0 0
BLACKSTONE GROUP L P COM UNIT LTD 09253U108 2,668 80,000 SH   DFND 1 80,000 0 0
BLACKSTONE MTG TR INC COM CL A 09257W100 39,743 1,257,700 SH   DFND 1 1,257,700 0 0
BLUEBIRD BIO INC COM 09609G100 210 2,000 SH   DFND 1 2,000 0 0
BOSTON SCIENTIFIC CORP COM 101137107 7,135 257,400 SH   DFND 1 257,400 0 0
BRISTOL MYERS SQUIBB CO COM 110122108 19,745 354,360 SH   DFND 1 354,360 0 0
BROADCOM LTD SHS Y09827109 41,253 177,015 SH   DFND 1 177,015 0 0
CABLE ONE INC COM 12685J105 1,999 2,812 SH   DFND 1 2,812 0 0
CAMBREX CORP COM 132011107 544 9,100 SH   DFND 1 9,100 0 0
CARDIOME PHARMA CORP COM NO PAR 14159U301 13,013 2,878,985 SH   DFND 1 2,878,985 0 0
CARVANA CO CL A 146869102 1,946 95,050 SH   DFND 1 95,050 0 0
CELGENE CORP COM 151020104 14,123 108,747 SH   DFND 1 108,747 0 0
CITIGROUP INC W EXP 01/04/201 172967226 41 271,800 SH   DFND 1 271,800 0 0
CITIGROUP INC COM NEW 172967424 69,016 1,031,943 SH   DFND 1 1,031,943 0 0
CLOVIS ONCOLOGY INC COM 189464100 986 10,535 SH   DFND 1 10,535 0 0
COGNIZANT TECHNOLOGY SOLUTIO CL A 192446102 22,490 338,700 SH   DFND 1 338,700 0 0
COHEN & STEERS GLOBAL INC BL COM 19248M103 210 22,043 SH   DFND 1 22,043 0 0
COMMUNITY HEALTHCARE TR INC COM 20369C106 5,898 230,500 SH   DFND 1 230,500 0 0
CREDIT ACCEP CORP MICH COM 225310101 30,461 118,459 SH   DFND 1 118,459 0 0
CREDIT SUISSE ASSET MGMT INC COM 224916106 146 43,421 SH   DFND 1 43,421 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 12,772 797,231 SH   DFND 1 797,231 0 0
D R HORTON INC COM 23331A109 33,419 966,695 SH   DFND 1 966,695 0 0
DERMIRA INC COM 24983L104 5,297 181,785 SH   DFND 1 181,785 0 0
DIVIDEND & INCOME FUND COM NEW 25538A204 883 71,500 SH   DFND 1 71,500 0 0
DOMINION RES INC VA NEW COM 25746U109 4,904 64,000 SH   DFND 1 64,000 0 0
DREYFUS HIGH YIELD STRATEGIE SH BEN INT 26200S101 183 52,318 SH   DFND 1 52,318 0 0
DUKE ENERGY CORP NEW COM NEW 26441C204 6,244 74,700 SH   DFND 1 74,700 0 0
EATON VANCE RISK MNGD DIV EQ COM 27829G106 440 47,000 SH   DFND 1 47,000 0 0
ELLIE MAE INC COM 28849P100 13,222 120,300 SH   DFND 1 120,300 0 0
ENVISION HEALTHCARE CORP COM 29414D100 4,087 65,209 SH   DFND 1 65,209 0 0
EVERSOURCE ENERGY COM 30040W108 5,033 82,900 SH   DFND 1 82,900 0 0
FACEBOOK INC CL A 30303M102 30,256 200,400 SH   DFND 1 200,400 0 0
FIRST REP BK SAN FRANCISCO C COM 33616C100 240 2,400 SH   DFND 1 2,400 0 0
FIRST TR ABERDEEN GLBL OPP F COM SHS 337319107 161 13,838 SH   DFND 1 13,838 0 0
FRANKLIN LTD DURATION INC TR COM 35472T101 427 36,100 SH   DFND 1 36,100 0 0
FRANKLIN RES INC COM 354613101 5,693 127,100 SH   DFND 1 127,100 0 0
GALAPAGOS NV SPON ADR 36315X101 5,345 69,853 SH   DFND 1 69,853 0 0
GENERAL AMERN INVS INC COM 368802104 883 25,700 SH   DFND 1 25,700 0 0
GLOBAL MED REIT INC COM NEW 37954A204 5,588 625,000 SH   DFND 1 625,000 0 0
GOLDMAN SACHS BDC INC SHS 38147U107 1,194 53,000 SH   DFND 1 53,000 0 0
GOLUB CAP BDC INC COM 38173M102 18,456 965,266 SH   DFND 1 965,266 0 0
GUGGENHEIM ENHNCD COM 40167B100 448 54,228 SH   DFND 1 54,228 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 4,809 47,971 SH   DFND 1 47,971 0 0
HOLOGIC INC COM 436440101 9,977 219,848 SH   DFND 1 219,848 0 0
IMAX CORP COM 45245E109 4,397 199,881 SH   DFND 1 199,881 0 0
INCYTE CORP COM 45337C102 630 5,000 SH   DFND 1 5,000 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101 4,680 376,850 SH   DFND 1 376,850 0 0
INTREXON CORP COM 46122T102 3,121 129,569 SH   DFND 1 129,569 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 922 21,700 SH   DFND 1 21,700 0 0
ISHARES TR MSCI INDIA ETF 46429B598 2,991 93,200 SH   DFND 1 93,200 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 1,011 6,500 SH   DFND 1 6,500 0 0
JPMORGAN CHASE & CO COM 46625H100 6,855 75,000 SH   DFND 1 75,000 0 0
KERYX BIOPHARMACEUTICALS INC COM 492515101 1,896 262,301 SH   DFND 1 262,301 0 0
KURA ONCOLOGY INC COM 50127T109 3,915 420,997 SH   DFND 1 420,997 0 0
LADDER CAP CORP CL A 505743104 14,268 1,063,978 SH   DFND 1 1,063,978 0 0
LAM RESEARCH CORP COM 512807108 12,234 86,500 SH   DFND 1 86,500 0 0
LANTHEUS HLDGS INC COM 516544103 1,091 61,800 SH   DFND 1 61,800 0 0
LATIN AMERN DISCOVERY FD INC COM 51828C106 168 16,000 SH   DFND 1 16,000 0 0
LEGG MASON BW GLB INC OPP FD COM 52469B100 167 12,607 SH   DFND 1 12,607 0 0
LENNAR CORP CL A 526057104 15,431 289,397 SH   DFND 1 289,397 0 0
LIBERTY ALL STAR EQUITY FD SH BEN INT 530158104 2,271 401,293 SH   DFND 1 401,293 0 0
LIBERTY BROADBAND CORP COM SER C 530307305 57,693 665,045 SH   DFND 1 665,045 0 0
LIBERTY INTERACTIVE CORP LBT VEN COM A NE 53071M856 63,846 1,220,992 SH   DFND 1 1,220,992 0 0
LOGMEIN INC COM 54142L109 13,641 130,534 SH   DFND 1 130,534 0 0
LUMENTUM HLDGS INC COM 55024U109 8,831 154,800 SH   DFND 1 154,800 0 0
MAXLINEAR INC CL A 57776J100 4,192 150,300 SH   DFND 1 150,300 0 0
MERCK & CO INC NEW COM 58933Y105 28,930 451,400 SH   DFND 1 451,400 0 0
MICROSOFT CORP COM 594918104 19,576 284,000 SH   DFND 1 284,000 0 0
MORGAN STANLEY CHINA A SH FD COM 617468103 785 35,100 SH   DFND 1 35,100 0 0
MTGE INVT CORP COM 55378A105 12,210 649,465 SH   DFND 1 649,465 0 0
NATIONAL GRID PLC SPONSORED ADR NE 636274409 2,637 41,983 SH   DFND 1 41,983 0 0
NETEASE INC SPONSORED ADR 64110W102 1,112 3,700 SH   DFND 1 3,700 0 0
NEUBERGER BERMAN INTER MUNI COM 64124P101 366 24,028 SH   DFND 1 24,028 0 0
NEUBERGER BERMAN RE ES SEC F COM 64190A103 1,259 233,200 SH   DFND 1 233,200 0 0
NEXPOINT CR STRATEGIES FD COM NEW 65340G205 1,079 49,531 SH   DFND 1 49,531 0 0
NUVASIVE INC COM 670704105 11,484 149,300 SH   DFND 1 149,300 0 0
NXSTAGE MEDICAL INC COM 67072V103 6,807 271,500 SH   DFND 1 271,500 0 0
ORBOTECH LTD ORD M75253100 6,155 188,684 SH   DFND 1 188,684 0 0
PACIRA PHARMACEUTICALS INC COM 695127100 930 19,500 SH   DFND 1 19,500 0 0
PENNYMAC MTG INVT TR COM 70931T103 25,629 1,401,272 SH   DFND 1 1,401,272 0 0
PFIZER INC COM 717081103 12,150 361,700 SH   DFND 1 361,700 0 0
PHYSICIANS RLTY TR COM 71943U104 2,739 136,000 SH   DFND 1 136,000 0 0
PIONEER HIGH INCOME TR COM 72369H106 685 69,300 SH   DFND 1 69,300 0 0
PRESTIGE BRANDS HLDGS INC COM 74112D101 1,776 33,630 SH   DFND 1 33,630 0 0
PULTE GROUP INC COM 745867101 21,667 883,294 SH   DFND 1 883,294 0 0
QUOTIENT LTD SHS G73268107 447 60,800 SH   DFND 1 60,800 0 0
SALESFORCE COM INC COM 79466L302 9,084 104,900 SH   DFND 1 104,900 0 0
SERVICE CORP INTL COM 817565104 7,723 230,868 SH   DFND 1 230,868 0 0
SOLAR CAP LTD COM 83413U100 23,688 1,083,131 SH   DFND 1 1,083,131 0 0
SOLAR SR CAP LTD COM 83416M105 2,252 134,500 SH   DFND 1 134,500 0 0
STARWOOD PPTY TR INC COM 85571B105 61,543 2,748,682 SH   DFND 1 2,748,682 0 0
TABLEAU SOFTWARE INC CL A 87336U105 5,484 89,500 SH   DFND 1 89,500 0 0
TARENA INTL INC ADR 876108101 605 33,800 SH   DFND 1 33,800 0 0
TOLL BROTHERS INC COM 889478103 348 8,800 SH   DFND 1 8,800 0 0
TPG SPECIALTY LENDING INC COM 87265K102 6,118 299,163 SH   DFND 1 299,163 0 0
TRI POINTE HOMES INC COM 87265H109 6,928 525,271 SH   DFND 1 525,271 0 0
UNITEDHEALTH GROUP INC COM 91324P102 371 2,000 SH   DFND 1 2,000 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 8,297 64,382 SH   DFND 1 64,382 0 0
VIASAT INC COM 92552V100 33,974 513,201 SH   DFND 1 513,201 0 0
VIPSHOP HLDGS LTD SPONSORED ADR 92763W103 13,619 1,290,858 SH   DFND 1 1,290,858 0 0
VIRTUS TOTAL RETURN FUND INC COM 92837G100 632 51,629 SH   DFND 1 51,629 0 0
VIRTUSA CORP COM 92827P102 697 23,700 SH   DFND 1 23,700 0 0
VOYA GLBL EQTY DIV & PREM OP COM 92912T100 86 11,400 SH   DFND 1 11,400 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 3,588 192,903 SH   DFND 1 192,903 0 0
WAYFAIR INC CL A 94419L101 5,189 67,500 SH   DFND 1 67,500 0 0
WELLS FARGO & CO NEW COM 949746101 233 4,200 SH   DFND 1 4,200 0 0
WELLS FARGO ADV GLB DIV OPP COM 94987C103 173 28,200 SH   DFND 1 28,200 0 0
WELLTOWER INC COM 95040Q104 9,491 126,800 SH   DFND 1 126,800 0 0
WESTERN ASSET CORPORATE LN F COM 95790J102 440 39,515 SH   DFND 1 39,515 0 0
WESTERN DIGITAL CORP COM 958102105 26,748 301,900 SH   DFND 1 301,900 0 0
WISDOMTREE TR INDIA ERNGS FD 97717W422 7,199 293,700 SH   DFND 1 293,700 0 0
YELP INC CL A 985817105 27,487 915,629 SH   DFND 1 915,629 0 0