The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABERDEEN AUSTRALIA EQTY FD I COM 003011103   167 27,500 SH   DFND 1 27,500 0 0
ABERDEEN EMERGING MKTS SMALL COM 00301T102   178 13,646 SH   DFND 1 13,646 0 0
ABERDEEN GTR CHINA FD INC COM 003031101   175 16,700 SH   DFND 1 16,700 0 0
ADAMS EXPRESS CO COM 006212104   3,019 219,530 SH   DFND 1 219,530 0 0
ADURO BIOTECH INC COM 00739L101   3,213 298,900 SH   DFND 1 298,900 0 0
AETNA INC NEW COM 00817Y108   1,046 8,200 SH   DFND 1 8,200 0 0
AKORN INC COM 009728106   11,688 485,371 SH   DFND 1 485,371 0 0
ALEXION PHARMACEUTICALS INC COM 015351109   15,119 124,700 SH   DFND 1 124,700 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102   20,919 194,000 SH   DFND 1 194,000 0 0
ALIGN TECHNOLOGY INC COM 016255101   19,891 173,400 SH   DFND 1 173,400 0 0
ALPHABET INC CAP STK CL A 02079K305   10,216 12,050 SH   DFND 1 12,050 0 0
ALPINE GLOBAL PREMIER PPTYS COM SBI 02083A103   1,970 344,332 SH   DFND 1 344,332 0 0
APPLE INC COM 037833100   112,400 782,400 SH   DFND 1 782,400 0 0
ARBOR RLTY TR INC COM 038923108   1,444 172,300 SH   DFND 1 172,300 0 0
ARES CAP CORP COM 04010L103   46,467 2,673,600 SH   DFND 1 2,673,600 0 0
ARES COML REAL ESTATE CORP COM 04013V108   4,672 349,200 SH   DFND 1 349,200 0 0
AVENUE INCOME CR STRATEGIES COM 05358E106   458 32,839 SH   DFND 1 32,839 0 0
B & G FOODS INC NEW COM 05508R106   205 5,100 SH   DFND 1 5,100 0 0
BAIDU INC SPON ADR REP A 056752108   12,858 74,530 SH   DFND 1 74,530 0 0
BANK AMER CORP COM 060505104   48,476 2,054,958 SH   DFND 1 2,054,958 0 0
BIOGEN INC COM 09062X103   15,406 56,344 SH   DFND 1 56,344 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101   9,086 103,509 SH   DFND 1 103,509 0 0
BLACKROCK RES & COMM STRAT T SHS 09257A108   606 70,500 SH   DFND 1 70,500 0 0
BLACKSTONE MTG TR INC COM CL A 09257W100   31,963 1,032,400 SH   DFND 1 1,032,400 0 0
BLUEBIRD BIO INC COM 09609G100   645 7,100 SH   DFND 1 7,100 0 0
BOSTON SCIENTIFIC CORP COM 101137107   6,402 257,400 SH   DFND 1 257,400 0 0
BRISTOL MYERS SQUIBB CO COM 110122108   21,148 388,886 SH   DFND 1 388,886 0 0
BROADCOM LTD SHS Y09827109   57,579 262,967 SH   DFND 1 262,967 0 0
CABLE ONE INC COM 12685J105   7,561 12,108 SH   DFND 1 12,108 0 0
CAMBREX CORP COM 132011107   501 9,100 SH   DFND 1 9,100 0 0
CARDIOME PHARMA CORP COM NO PAR 14159U301   8,905 2,958,415 SH   DFND 1 2,958,415 0 0
CARTER INC COM 146229109   242 2,700 SH   DFND 1 2,700 0 0
CELGENE CORP COM 151020104   12,194 98,000 SH   DFND 1 98,000 0 0
CITIGROUP INC W EXP 01/04/201 172967226   40 271,800 SH   DFND 1 271,800 0 0
CITIGROUP INC COM NEW 172967424   49,785 832,243 SH   DFND 1 832,243 0 0
CLOVIS ONCOLOGY INC COM 189464100   1,012 15,900 SH   DFND 1 15,900 0 0
COGNIZANT TECHNOLOGY SOLUTIO CL A 192446102   13,053 219,300 SH   DFND 1 219,300 0 0
COHEN & STEERS GLOBAL INC BL COM 19248M103   202 22,043 SH   DFND 1 22,043 0 0
COHEN & STEERS QUALITY RLTY COM 19247L106   317 25,800 SH   DFND 1 25,800 0 0
COMMUNITY HEALTHCARE TR INC COM 20369C106   4,414 184,700 SH   DFND 1 184,700 0 0
CREDIT ACCEP CORP MICH COM 225310101   24,412 122,420 SH   DFND 1 122,420 0 0
CREDIT SUISSE ASSET MGMT INC COM 224916106   307 93,095 SH   DFND 1 93,095 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108   17,919 824,864 SH   DFND 1 824,864 0 0
D R HORTON INC COM 23331A109   33,375 1,001,943 SH   DFND 1 1,001,943 0 0
DERMIRA INC COM 24983L104   8,691 254,785 SH   DFND 1 254,785 0 0
DOMINION RES INC VA NEW COM 25746U109   4,398 56,700 SH   DFND 1 56,700 0 0
DOUBLELINE INCOME SOLUTIONS COM 258622109   1,082 53,900 SH   DFND 1 53,900 0 0
DOUBLELINE OPPORTUNISTIC CR COM 258623107   702 29,420 SH   DFND 1 29,420 0 0
DREYFUS HIGH YIELD STRATEGIE SH BEN INT 26200S101   811 239,107 SH   DFND 1 239,107 0 0
DUFF & PHELPS GLB UTL INC FD COM 26433C105   407 25,000 SH   DFND 1 25,000 0 0
DUKE ENERGY CORP NEW COM NEW 26441C204   5,560 67,800 SH   DFND 1 67,800 0 0
EATON VANCE TAX MNGD GBL DV COM 27829F108   6,526 765,954 SH   DFND 1 765,954 0 0
EATON VANCE TX MGD DIV EQ IN COM 27828N102   2,177 196,653 SH   DFND 1 196,653 0 0
EDITAS MEDICINE INC COM 28106W103   8,751 392,087 SH   DFND 1 392,087 0 0
ELLIE MAE INC COM 28849P100   12,433 124,000 SH   DFND 1 124,000 0 0
ENVISION HEALTHCARE CORP COM 29414D100   8,463 138,009 SH   DFND 1 138,009 0 0
EVERSOURCE ENERGY COM 30040W108   4,314 73,400 SH   DFND 1 73,400 0 0
FINISAR CORP COM NEW 31787A507   7,226 264,300 SH   DFND 1 264,300 0 0
FIRST TR ABERDEEN GLBL OPP F COM SHS 337319107   579 49,806 SH   DFND 1 49,806 0 0
FIRST TR DYNAMIC EUROPE EQT COM SHS 33740D107   908 52,600 SH   DFND 1 52,600 0 0
FLAHERTY&CRMN PFD SEC INCOM COM 338478100   639 31,100 SH   DFND 1 31,100 0 0
FRANKLIN RES INC COM 354613101   9,326 221,300 SH   DFND 1 221,300 0 0
GABELLI CONV&INCOM SECS FD I COM 36240B109   178 36,343 SH   DFND 1 36,343 0 0
GABELLI EQUITY TR INC COM 362397101   216 36,120 SH   DFND 1 36,120 0 0
GABELLI MULTIMEDIA TR INC COM 36239Q109   166 20,600 SH   DFND 1 20,600 0 0
GALAPAGOS NV SPON ADR 36315X101   6,453 74,870 SH   DFND 1 74,870 0 0
GLOBAL MED REIT INC COM NEW 37954A204   5,675 625,000 SH   DFND 1 625,000 0 0
GOLDMAN SACHS BDC INC SHS 38147U107   1,306 53,000 SH   DFND 1 53,000 0 0
GOLUB CAP BDC INC COM 38173M102   19,189 965,266 SH   DFND 1 965,266 0 0
GUGGENHEIM ENHNCD COM 40167B100   192 23,728 SH   DFND 1 23,728 0 0
GW PHARMACEUTICALS PLC ADS 36197T103   11,876 98,200 SH   DFND 1 98,200 0 0
HERCULES TECH GROWTH CAP INC COM 427096508   5,851 386,700 SH   DFND 1 386,700 0 0
HOLOGIC INC COM 436440101   18,548 435,900 SH   DFND 1 435,900 0 0
IMAX CORP COM 45245E109   23,952 704,476 SH   DFND 1 704,476 0 0
INCYTE CORP COM 45337C102   789 5,900 SH   DFND 1 5,900 0 0
INTELLIA THERAPEUTICS INC COM 45826J105   600 42,600 SH   DFND 1 42,600 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101   14,605 898,750 SH   DFND 1 898,750 0 0
INTREXON CORP COM 46122T102   2,711 136,774 SH   DFND 1 136,774 0 0
ISHARES TR MSCI INDIA ETF 46429B598   2,934 93,200 SH   DFND 1 93,200 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105   3,512 24,200 SH   DFND 1 24,200 0 0
KERYX BIOPHARMACEUTICALS INC COM 492515101   657 106,700 SH   DFND 1 106,700 0 0
KURA ONCOLOGY INC COM 50127T109   4,406 500,697 SH   DFND 1 500,697 0 0
LADDER CAP CORP CL A 505743104   15,540 1,076,178 SH   DFND 1 1,076,178 0 0
LATIN AMERN DISCOVERY FD INC COM 51828C106   338 32,100 SH   DFND 1 32,100 0 0
LENNAR CORP CL A 526057104   15,294 298,779 SH   DFND 1 298,779 0 0
LIBERTY ALL STAR EQUITY FD SH BEN INT 530158104   2,019 369,793 SH   DFND 1 369,793 0 0
LIBERTY BROADBAND CORP COM SER C 530307305   54,583 631,745 SH   DFND 1 631,745 0 0
LIBERTY INTERACTIVE CORP LBT VEN COM A NE 53071M856   44,017 989,592 SH   DFND 1 989,592 0 0
LIONS GATE ENTMNT CORP CL B NON VTG 535919500   1,648 67,600 SH   DFND 1 67,600 0 0
LIONS GATE ENTMNT CORP CL A VTG 535919401   2,744 103,300 SH   DFND 1 103,300 0 0
LOGMEIN INC COM 54142L109   14,121 144,834 SH   DFND 1 144,834 0 0
LUMENTUM HLDGS INC COM 55024U109   5,856 109,766 SH   DFND 1 109,766 0 0
MAXLINEAR INC CL A 57776J100   5,324 189,800 SH   DFND 1 189,800 0 0
MERCK & CO INC NEW COM 58933Y105   28,618 450,400 SH   DFND 1 450,400 0 0
MICROSOFT CORP COM 594918104   26,555 403,200 SH   DFND 1 403,200 0 0
MONRO MUFFLER BRAKE INC COM 610236101   406 7,800 SH   DFND 1 7,800 0 0
MORGAN STANLEY CHINA A SH FD COM 617468103   675 35,100 SH   DFND 1 35,100 0 0
MTGE INVT CORP COM 55378A105   11,247 671,465 SH   DFND 1 671,465 0 0
NATIONAL GRID PLC SPON ADR NEW 636274300   2,907 45,800 SH   DFND 1 45,800 0 0
NETEASE INC SPONSORED ADR 64110W102   1,051 3,700 SH   DFND 1 3,700 0 0
NEUBERGER BERMAN INTER MUNI COM 64124P101   177 11,900 SH   DFND 1 11,900 0 0
NUVEEN ALL CAP ENE MLP OPPO COM 67075E108   158 15,000 SH   DFND 1 15,000 0 0
NUVEEN FLOATING RATE INCOME COM 67072T108   538 46,700 SH   DFND 1 46,700 0 0
NXSTAGE MEDICAL INC COM 67072V103   5,696 212,300 SH   DFND 1 212,300 0 0
ORBOTECH LTD ORD M75253100   6,756 209,500 SH   DFND 1 209,500 0 0
PACHOLDER HIGH YIELD FD INC COM 693742108   958 124,140 SH   DFND 1 124,140 0 0
PACIRA PHARMACEUTICALS INC COM 695127100   1,040 22,800 SH   DFND 1 22,800 0 0
PARSLEY ENERGY INC CL A 701877102   10,142 311,967 SH   DFND 1 311,967 0 0
PENNYMAC MTG INVT TR COM 70931T103   19,812 1,116,172 SH   DFND 1 1,116,172 0 0
PFIZER INC COM 717081103   12,374 361,700 SH   DFND 1 361,700 0 0
PHYSICIANS RLTY TR COM 71943U104   2,702 136,000 SH   DFND 1 136,000 0 0
PIONEER HIGH INCOME TR COM 72369H106   684 69,300 SH   DFND 1 69,300 0 0
PRESTIGE BRANDS HLDGS INC COM 74112D101   2,061 37,100 SH   DFND 1 37,100 0 0
PRINCIPAL REAL ESTATE INCOME SHS BEN INT 74255X104   435 24,812 SH   DFND 1 24,812 0 0
PULTE GROUP INC COM 745867101   21,657 919,621 SH   DFND 1 919,621 0 0
ROLLINS INC COM 775711104   241 6,500 SH   DFND 1 6,500 0 0
ROYCE VALUE TR INC COM 780910105   387 27,641 SH   DFND 1 27,641 0 0
RSP PERMIAN INC COM 74978Q105   4,002 96,600 SH   DFND 1 96,600 0 0
SALESFORCE COM INC COM 79466L302   10,682 129,500 SH   DFND 1 129,500 0 0
SERVICE CORP INTL COM 817565104   9,713 314,532 SH   DFND 1 314,532 0 0
SOLAR CAP LTD COM 83413U100   18,666 825,572 SH   DFND 1 825,572 0 0
SOLAR SR CAP LTD COM 83416M105   2,418 134,500 SH   DFND 1 134,500 0 0
STARWOOD PPTY TR INC COM 85571B105   42,626 1,887,782 SH   DFND 1 1,887,782 0 0
SYNERON MEDICAL LTD ORD SHS M87245102   1,209 114,600 SH   DFND 1 114,600 0 0
T MOBILE US INC COM 872590104   18,988 293,980 SH   DFND 1 293,980 0 0
TARENA INTL INC ADR 876108101   631 33,800 SH   DFND 1 33,800 0 0
TPG SPECIALTY LENDING INC COM 87265K102   6,263 307,163 SH   DFND 1 307,163 0 0
TRI POINTE HOMES INC COM 87265H109   7,085 564,971 SH   DFND 1 564,971 0 0
UNITEDHEALTH GROUP INC COM 91324P102   328 2,000 SH   DFND 1 2,000 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   7,195 65,800 SH   DFND 1 65,800 0 0
VIASAT INC COM 92552V100   33,984 532,501 SH   DFND 1 532,501 0 0
VIRTUSA CORP COM 92827P102   6,089 201,500 SH   DFND 1 201,500 0 0
VOYA GLBL EQTY DIV & PREM OP COM 92912T100   851 115,900 SH   DFND 1 115,900 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105   5,415 196,903 SH   DFND 1 196,903 0 0
WAYFAIR INC CL A 94419L101   4,069 100,482 SH   DFND 1 100,482 0 0
WELLS FARGO ADV GLB DIV OPP COM 94987C103   424 72,800 SH   DFND 1 72,800 0 0
WELLS FARGO ADVANTAGE MULTI COM SHS 94987D101   925 69,400 SH   DFND 1 69,400 0 0
WELLTOWER INC COM 95040Q104   7,153 101,000 SH   DFND 1 101,000 0 0
WISDOMTREE TR INDIA ERNGS FD 97717W422   7,570 313,700 SH   DFND 1 313,700 0 0
YELP INC CL A 985817105   27,344 834,929 SH   DFND 1 834,929 0 0
ZWEIG FD COM NEW 989834205   2,377 213,762 SH   DFND 1 213,762 0 0
STARWOOD PPTY TR INC COM 85571B105   38,715 1,763,763 SH   DFND 1 1,763,763 0 0
SYNERON MEDICAL LTD ORD SHS M87245102   543 64,700 SH   DFND 1 64,700 0 0
T MOBILE US INC COM 872590104   10,293 178,980 SH   DFND 1 178,980 0 0
TARENA INTL INC ADR 876108101   268 17,900 SH   DFND 1 17,900 0 0
TEKLA LIFE SCIENCES INVS SH BEN INT 87911K100   825 48,545 SH   DFND 1 48,545 0 0
THERAPEUTICSMD INC COM 88338N107   2,115 366,550 SH   DFND 1 366,550 0 0
TPG SPECIALTY LENDING INC COM 87265K102   3,301 176,700 SH   DFND 1 176,700 0 0
TRANSDIGM GROUP INC COM 893641100   22,730 91,300 SH   DFND 1 91,300 0 0
TRI POINTE HOMES INC COM 87265H109   4,035 351,471 SH   DFND 1 351,471 0 0
TWO HBRS INVT CORP COM 90187B101   8,574 983,303 SH   DFND 1 983,303 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102   645 4,500 SH   DFND 1 4,500 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   8,056 109,348 SH   DFND 1 109,348 0 0
VIASAT INC COM 92552V100   38,499 581,380 SH   DFND 1 581,380 0 0
VIRTUSA CORP COM 92827P102   5,509 219,300 SH   DFND 1 219,300 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105   5,520 211,103 SH   DFND 1 211,103 0 0
WAYFAIR INC CL A 94419L101   7,647 218,182 SH   DFND 1 218,182 0 0
WELLS FARGO ADVANTAGE MULTI COM SHS 94987D101   409 31,900 SH   DFND 1 31,900 0 0
WELLTOWER INC COM 95040Q104   10,347 154,600 SH   DFND 1 154,600 0 0
WISDOMTREE TR INDIA ERNGS FD 97717W422   832 41,200 SH   DFND 1 41,200 0 0
WNS HOLDINGS LTD SPON ADR 92932M101   4,650 168,800 SH   DFND 1 168,800 0 0
YELP INC CL A 985817105   17,762 465,829 SH   DFND 1 465,829 0 0
ZELTIQ AESTHETICS INC COM 98933Q108   357 8,200 SH   DFND 1 8,200 0 0
ZWEIG FD COM NEW 989834205   191 15,800 SH   DFND 1 15,800 0 0