Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Cash flows from operating activities
Net loss	$ (17,332)	$ (40,506)
Income from discontinued operations	3,935	20,261
Loss from continuing operations	(21,267)	(60,767)
Adjustments to reconcile net loss to net cash used in operating activities
Non-cash interest expense	141	240
Purchased premiums and interest on marketable securities		(2)
Amortization and accretion on marketable securities	(292)	(651)
Loss on extinguishment of debt	971
Non-cash activity related to discontinued operations		(171)
Benefit from intra-period tax allocation	(1,500)	(7,695)
Loss on disposal of property and equipment		167
Gain on sale of property and equipment	(1,984)
Gain on sale of in progress research and development asset	(3,500)
Depreciation and amortization expense	2,228	4,074
Stock-based compensation expense	2,371	3,050
(Gain) loss on equity method investment	(372)	3,123
Changes in operating assets and liabilities:
Accounts receivable		100
Prepaid expenses and other assets	3,917	(993)
Accounts payable, accrued expenses and other	(12,081)	(3,801)
Deferred rent		(2,262)
Net cash used in operating activities	(31,368)	(65,588)
Cash flows from investing activities
Purchase of marketable securities		(103,055)
Proceeds from sales and maturities of marketable securities	51,500	52,500
Purchase of property and equipment		(118)
Proceeds from sale of in progress research and development asset	3,500
Proceeds from sale of equity method investment	7,800
Proceeds from sale of property and equipment	2,025	75
Proceeds from sale of a discontinued operation	5,000	28,000
Net cash provided by (used in) investing activities	69,825	(22,598)
Cash flows from financing activities
Proceeds from exercise of options	145
Proceeds from issuance of note payable, net of issuance costs		14,632
Repayment of debt	(15,000)
Payment of debt extinguishment costs	(985)
Payment of dividends	(26,700)
Net cash (used in) provided by financing activities	(42,540)	14,632
Net decrease in cash, cash equivalents and restricted cash	(4,083)	(73,554)
Cash, cash equivalents and restricted cash, beginning of period	20,663	94,217
Cash, cash equivalents and restricted cash, end of period	16,580	20,663
Supplemental disclosure of cash flows
Cash paid for income taxes		390
Cash paid for interest	$ 1,400	$ 586