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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Cash flows from operating activities    
Net loss $ (20,593) $ (31,562)
Gain from discontinued operations   16,330
Loss from continuing operations (20,593) (47,892)
Adjustments to reconcile net loss to net cash used in operating activities    
Non-cash interest expense 141 121
Loss on extinguishment of debt 971  
Benefit from intraperiod tax allocation   (4,798)
Depreciation and amortization expense 2,228 3,211
Non-cash activity related to discontinued operations   (532)
Loss (gain) on sale of equipment (1,984) 184
Gain on sale of in progress research and development asset (3,500)  
Premiums paid on marketable securities   (2)
Amortization and accretion on marketable securities (292) (398)
Stock-based compensation expense 1,784 2,326
Loss (gain) on equity method investment (372) 1,658
Changes in operating assets and liabilities:    
Prepaid expenses and other assets 3,001 (314)
Income taxes payable   361
Accounts payable, accrued expenses and other (10,112) 1,083
Deferred rent   (1,704)
Net cash used in operating activities (28,728) (46,696)
Cash flows from investing activities    
Purchase of property and equipment   (118)
Proceeds from sale of equipment 2,025  
Proceeds from sale of in progress research and development asset 3,500  
Proceeds from sale of equity method investment 7,800  
Proceeds from sale of business   23,000
Proceeds from maturities and sales of marketable securities 51,500 42,200
Purchases of marketable securities   (76,857)
Net cash provided by (used in) investing activities 64,825 (11,775)
Cash flows from financing activities    
Proceeds from issuance of notes payable, net of issuance costs   14,632
Proceeds from exercise of stock options 83  
Repayment of debt (15,000)  
Payment of debt extinguishment costs (985)  
Payment of dividend (20,000)  
Net cash (used in) provided by financing activities (35,902) 14,632
Net increase (decrease) in cash, cash equivalents and restricted cash 195 (43,839)
Cash, cash equivalents and restricted cash, beginning of period 20,663 94,217
Cash, cash equivalents and restricted cash, end of period 20,858 50,378
Supplemental disclosure of cash flows    
Cash paid for interest $ 1,399 $ 235