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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Cash flows from operating activities    
Net loss $ (19,888) $ (35,551)
Adjustments to reconcile net loss to net cash used in operating activities    
Non-cash interest expense 141  
Loss on extinguishment of debt 971  
Depreciation and amortization expense 2,228 2,258
Loss (gain) on sale of equipment (1,984) 184
Premiums paid on marketable securities   (40)
Amortization and accretion on marketable securities (279) (223)
Stock-based compensation expense 1,081 1,544
Loss (gain) on equity method investment (372) 1,417
Changes in operating assets and liabilities:    
Prepaid expenses and other assets 2,432 (79)
Accounts payable, accrued expenses and other (9,855) (2,037)
Deferred rent   (1,055)
Net cash used in operating activities (25,525) (33,582)
Cash flows from investing activities    
Purchase of property and equipment   (118)
Proceeds from sale of equipment 2,025  
Proceeds from sale of equity method investment 7,800  
Proceeds from maturities and sales of marketable securities 48,500 11,050
Purchases of marketable securities   (48,331)
Net cash provided by (used in) investing activities 58,325 (37,399)
Cash flows from financing activities    
Proceeds from exercise of stock options 23  
Repayment of debt (15,000)  
Payment of debt extinguishment costs (985)  
Net cash used in financing activities (15,962)  
Net increase (decrease) in cash, cash equivalents and restricted cash 16,838 (70,981)
Cash, cash equivalents and restricted cash, beginning of period 20,663 94,217
Cash, cash equivalents and restricted cash, end of period 37,501 $ 23,236
Supplemental disclosure of cash flows    
Cash paid for interest $ 1,399