Discontinued Operations - Sale of Commercial Business - Additional Information (Detail)	12 Months Ended
Dec. 31, 2018 USD ($)
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items]
Discontinued operations, amounts directly relate to commercial bussiness	$ 28,000,000
Research and development expense	200,000
Asset Sale Agreement [Member] \| Development and Commercialization Milestones [Member]
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items]
Maximum amount of milestone payments that can be received	33,000,000
Milestone payment received	$ 28,000,000

Disposal group including discontinued operation research and development expenses.

No definition available.

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- Definition

Represents the maximum cumulative amount of milestone payments that can be received over the life of the license and collaboration agreements.

+ References

No definition available.

+ Details

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- Definition

Amount before tax of gain (loss) not previously recognized resulting from the disposal of a discontinued operation.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 1
-Subparagraph (b)
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Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
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-Section 45
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-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 45
-Paragraph 3B
-URI http://asc.fasb.org/extlink&oid=109222160&loc=SL51721525-107759

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

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- Definition

The amount of consideration recognized during the period for the milestone or milestones.

+ References

No definition available.

+ Details

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