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Investment in Silver Creek - Additional Information (Detail) - USD ($)
$ in Thousands
Sep. 30, 2018
Dec. 31, 2017
Sep. 30, 2017
Consolidation Less Than Wholly Owned Subsidiary Parent Ownership Interest Effects Of Changes Net [Line Items]      
Equity method investment $ 8,893 $ 10,551  
Silver Creek Pharmaceuticals Inc [Member]      
Consolidation Less Than Wholly Owned Subsidiary Parent Ownership Interest Effects Of Changes Net [Line Items]      
Equity method investment $ 8,900    
Silver Creek Pharmaceuticals Inc [Member] | Maximum [Member]      
Consolidation Less Than Wholly Owned Subsidiary Parent Ownership Interest Effects Of Changes Net [Line Items]      
Ownership interest percentage held by parent     50.00%