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Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Sep. 30, 2017
Summary Of Significant Accounting Policies [Line Items]          
Discontinued operations $ 0 $ 540,485,000 $ 0 $ 539,538,000  
Maximum [Member] | Silver Creek Pharmaceuticals Inc [Member]          
Summary Of Significant Accounting Policies [Line Items]          
Ownership interest (as a percent)         50.00%