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Investment in Silver Creek - Additional Information (Detail) - USD ($)
$ in Thousands
12 Months Ended
Jul. 14, 2017
Dec. 31, 2017
Sep. 30, 2017
Dec. 31, 2016
Consolidation Less Than Wholly Owned Subsidiary Parent Ownership Interest Effects Of Changes Net [Line Items]        
Gain on deconsolidation   $ 10,848    
Equity method investment   10,551    
Loss on equity method investment   (849)    
Silver Creek Pharmaceuticals Inc [Member]        
Consolidation Less Than Wholly Owned Subsidiary Parent Ownership Interest Effects Of Changes Net [Line Items]        
Ownership interest percentage held     43.00%  
Gain on deconsolidation   10,848    
Investment at fair value $ 11,400 11,400    
Equity method investment   10,600    
Loss on equity method investment   $ 800    
Silver Creek Pharmaceuticals Inc [Member] | Minimum [Member]        
Consolidation Less Than Wholly Owned Subsidiary Parent Ownership Interest Effects Of Changes Net [Line Items]        
Ownership interest percentage held by parent and its de facto agents       50.00%
Silver Creek Pharmaceuticals Inc [Member] | Maximum [Member]        
Consolidation Less Than Wholly Owned Subsidiary Parent Ownership Interest Effects Of Changes Net [Line Items]        
Ownership interest percentage held by parent     50.00%