Property and Equipment, Net (Tables)

12 Months Ended

Dec. 31, 2017

Property Plant And Equipment [Abstract]

Schedule of Property and Equipment, Net

Property and equipment, net as of December 31, 2017 and 2016 consisted of the following:

	December 31,
(in thousands)	2017			2016
Lab equipment	$	13,486		$	17,537
IT equipment		3,853			8,509
Leasehold improvements		20,790			20,633
Furniture and fixtures		335			626
Construction in process		30			378
Total property and equipment, gross		38,494			47,683
Less: Accumulated depreciation		(32,027	)		(33,471	)
Total property and equipment, net	$	6,467		$	14,212