Accounts Payable, Accrued Expenses and Other - Schedule of Accounts Payable, Accrued Expenses and Other (Detail) - USD ($) $ in Thousands	Dec. 31, 2015	Dec. 31, 2014
Payables and Accruals [Abstract]
Accounts payable	$ 5,049	$ 2,510
Accrued goods and services	14,295	17,481
Accrued clinical trial costs	12,764	7,637
Accrued drug purchase costs	7,460
Accrued payroll and related benefits	9,009	6,166
Accrued interest	3,041	2,956
Accrued dividends payable	19	19
Deferred tax incentives	445	467
Total accounts payable, accrued expenses and other	$ 52,082	$ 37,236