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Property and Equipment, Net (Tables)
12 Months Ended
Dec. 31, 2015
Property, Plant and Equipment [Abstract]  
Schedule of Property and Equipment, Net

Property and equipment, net as of December 31, 2015 and 2014 consisted of the following:

 

     December 31,  
(in thousands)    2015      2014  

Lab equipment

   $ 19,305       $ 16,214   

IT equipment

     7,742         3,113   

Leasehold improvements

     21,026         18,219   

Furniture and fixtures

     910         624   

Construction in process

     2,243         472   
  

 

 

    

 

 

 

Total property and equipment, gross

     51,226         38,642   

Less: Accumulated depreciation

     (29,311      (24,140
  

 

 

    

 

 

 

Total property and equipment, net

   $ 21,915       $ 14,502