Accounts Payable, Accrued Expenses and Other - Schedule of Accounts Payable, Accrued Expenses and Other (Detail) - USD ($) $ in Thousands	Sep. 30, 2015	Dec. 31, 2014
Payables and Accruals [Abstract]
Accounts payable	$ 6,245	$ 2,510
Accrued goods and services	13,054	12,481
Accrued clinical trial costs	9,538	7,637
Accrued payroll and related benefits	7,805	6,166
Accrued interest	1,538	2,956
Accrued dividends payable	19	19
Accrued milestone payment owed to PharmaEngine		5,000
Deferred tax incentives	503	467
Total accounts payable, accrued expenses and other	$ 38,702	$ 37,236