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License and Collaboration Agreements (Tables)
6 Months Ended
Jun. 30, 2015
Sanofi [Member]  
Schedule of Revenue Recognized and Assets and Liabilities under Collaborative Arrangements

During the three and six months ended June 30, 2015, the Company recognized no revenue under the Sanofi Agreement. During the three and six months ended June 30, 2014, the Company recognized revenue based on the following components of the Sanofi Agreement:

 

(in thousands)    Three months ended
June 30,

2014
     Six months ended
June 30,

2014
 

Upfront payment

   $ 13,268       $ 14,518   

Milestone payments

     5,529         6,049   

Development services

     3,040         13,740   

Manufacturing services and other

     5,978         6,542   
  

 

 

    

 

 

 

Total

   $ 27,815       $ 40,849   

 

As of June 30, 2015, the Company maintained no assets or liabilities related to the Sanofi Agreement. As of December 31, 2014, the Company maintained the following assets and liabilities related to the Sanofi Agreement:

 

(in thousands)    As of
December 31, 2014
 

Accounts receivable, billed

   $ 369   

Accounts receivable, unbilled

     1,282   

Deferred revenue

     —     

Baxalta [Member]  
Schedule of Revenue Recognized and Assets and Liabilities under Collaborative Arrangements

During the three and six months ended June 30, 2015, the Company recognized revenue based on the following components of the Baxalta Agreement:

 

(in thousands)    Three months ended
June 30,

2015
     Six months ended
June 30,

2015
 

Proportional Performance Model

   $ 16,558       $ 31,399   

Substantive Milestones

     20,000         20,000   
  

 

 

    

 

 

 

Total

   $ 36,558       $ 51,399   

 

As of June 30, 2015 and December 31, 2014, the Company maintained the following assets and liabilities related to the Baxalta Agreement:

 

(in thousands)    As of
June 30, 2015
    

As of

December 31, 2014

 

Accounts receivable, billed

   $ 807       $ —     

Accounts receivable, unbilled

     907         1,615   

Deferred revenue

   $ 64,611       $ 91,156