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Fair Value of Financial Instruments - Additional Information (Detail) (USD $)
3 Months Ended
Mar. 31, 2015
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]  
Marketable securities with an original maturity Greater than three months
Hercules [Member]  
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]  
Carrying value of debt 40,600,000us-gaap_LongTermDebt
/ dei_LegalEntityAxis
= mack_HerculesTechnologyGrowthCapitalIncMember
Level 3 [Member] | Hercules [Member]  
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]  
Fair value of debt 40,800,000us-gaap_LongTermDebtFairValue
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel3Member
/ dei_LegalEntityAxis
= mack_HerculesTechnologyGrowthCapitalIncMember
Senior Convertible Notes [Member]  
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]  
Principal amount 125,000,000us-gaap_DebtInstrumentFaceAmount
/ us-gaap_LongtermDebtTypeAxis
= us-gaap_SeniorNotesMember
Carrying value of debt 82,600,000us-gaap_LongTermDebt
/ us-gaap_LongtermDebtTypeAxis
= us-gaap_SeniorNotesMember
Senior Convertible Notes [Member] | Level 2 [Member]  
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]  
Fair value of debt 253,500,000us-gaap_LongTermDebtFairValue
/ us-gaap_FairValueByFairValueHierarchyLevelAxis
= us-gaap_FairValueInputsLevel2Member
/ us-gaap_LongtermDebtTypeAxis
= us-gaap_SeniorNotesMember
Maximum [Member]  
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]  
Liquid investments with an original maturity 3 months