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Condensed Consolidated Balance Sheets (USD $)
In Thousands, unless otherwise specified
Mar. 31, 2015
Dec. 31, 2014
Current assets:    
Cash and cash equivalents $ 28,833us-gaap_CashAndCashEquivalentsAtCarryingValue $ 35,688us-gaap_CashAndCashEquivalentsAtCarryingValue
Available-for-sale securities 62,938us-gaap_MarketableSecuritiesCurrent 88,340us-gaap_MarketableSecuritiesCurrent
Restricted cash 101us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue 101us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue
Accounts receivable 4,248us-gaap_ReceivablesNetCurrent 3,313us-gaap_ReceivablesNetCurrent
Prepaid expenses and other current assets 3,178us-gaap_PrepaidExpenseAndOtherAssetsCurrent 4,654us-gaap_PrepaidExpenseAndOtherAssetsCurrent
Total current assets 99,298us-gaap_AssetsCurrent 132,096us-gaap_AssetsCurrent
Restricted cash 584us-gaap_RestrictedCashAndCashEquivalentsNoncurrent 584us-gaap_RestrictedCashAndCashEquivalentsNoncurrent
Property and equipment, net 15,749us-gaap_PropertyPlantAndEquipmentNet 14,502us-gaap_PropertyPlantAndEquipmentNet
Other assets 139us-gaap_OtherAssetsNoncurrent 144us-gaap_OtherAssetsNoncurrent
Intangible assets, net 1,445us-gaap_FiniteLivedIntangibleAssetsNet 1,525us-gaap_FiniteLivedIntangibleAssetsNet
In-process research and development 6,200us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill 6,200us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill
Goodwill 3,605us-gaap_Goodwill 3,605us-gaap_Goodwill
Total assets 127,020us-gaap_Assets 158,656us-gaap_Assets
Current liabilities:    
Accounts payable, accrued expenses and other 42,979us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent 37,236us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent
Deferred revenues 59,506us-gaap_DeferredRevenueCurrent 59,275us-gaap_DeferredRevenueCurrent
Deferred rent 1,224us-gaap_DeferredRentCreditCurrent 1,285us-gaap_DeferredRentCreditCurrent
Long-term debt, current portion   13,346us-gaap_LongTermDebtCurrent
Total current liabilities 103,709us-gaap_LiabilitiesCurrent 111,142us-gaap_LiabilitiesCurrent
Deferred revenues, net of current portion 23,229us-gaap_DeferredRevenueNoncurrent 35,682us-gaap_DeferredRevenueNoncurrent
Deferred rent, net of current portion 5,156us-gaap_DeferredRentCreditNoncurrent 5,401us-gaap_DeferredRentCreditNoncurrent
Deferred tax incentives, net of current portion 468us-gaap_DeferredCreditsAndOtherLiabilitiesNoncurrent 496us-gaap_DeferredCreditsAndOtherLiabilitiesNoncurrent
Long-term debt, net of current portion 122,080us-gaap_LongTermDebtNoncurrent 106,806us-gaap_LongTermDebtNoncurrent
Accrued interest 1,200mack_InterestPayableNoncurrent 1,200mack_InterestPayableNoncurrent
Total liabilities 255,842us-gaap_Liabilities 260,727us-gaap_Liabilities
Commitments and contingencies (Note 10)      
Non-controlling interest 396us-gaap_MinorityInterest 69us-gaap_MinorityInterest
Stockholders' deficit:    
Preferred stock, $0.01 par value: 10,000 shares authorized at March 31, 2015 and December 31, 2014; no shares issued or outstanding at March 31, 2015 or December 31, 2014      
Common stock, $0.01 par value: 200,000 shares authorized at March 31, 2015 and December 31, 2014; 109,386 and 106,697 shares issued and outstanding at March 31, 2015 and December 31, 2014, respectively 1,094us-gaap_CommonStockValue 1,067us-gaap_CommonStockValue
Additional paid-in capital 559,175us-gaap_AdditionalPaidInCapital 552,037us-gaap_AdditionalPaidInCapital
Accumulated other comprehensive loss (27)us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax (74)us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax
Accumulated deficit (689,460)us-gaap_RetainedEarningsAccumulatedDeficit (655,170)us-gaap_RetainedEarningsAccumulatedDeficit
Total stockholders' deficit (129,218)us-gaap_StockholdersEquity (102,140)us-gaap_StockholdersEquity
Total liabilities, non-controlling interest and stockholders' deficit $ 127,020us-gaap_LiabilitiesAndStockholdersEquity $ 158,656us-gaap_LiabilitiesAndStockholdersEquity