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Stock-Based Compensation (Details 3) (USD $) In Thousands, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2013	Sep. 30, 2012	Sep. 30, 2013	Sep. 30, 2012
Allocation of recognized period cost
Stock-based compensation expense for employee awards	$ 2,729	$ 1,800	$ 8,062	$ 4,516
Stock-based compensation expense for non-employee awards	(192)	383	(109)	416
Total stock-based compensation expense	2,537	2,183	7,953	4,932
Research and development
Allocation of recognized period cost
Stock-based compensation expense for employee awards	1,517	1,119	4,453	2,972
General and administrative
Allocation of recognized period cost
Stock-based compensation expense for employee awards	$ 1,212	$ 681	$ 3,609	$ 1,544

Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

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