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Stock-Based Compensation (Details 3) (USD $) In Thousands, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2013	Jun. 30, 2012	Jun. 30, 2013	Jun. 30, 2012
Allocation of recognized period cost
Stock-based compensation expense for employee awards	$ 2,958	$ 1,377	$ 5,332	$ 2,715
Stock-based compensation expense for non-employee awards	72	33	84	34
Total stock-based compensation expense	3,030	1,410	5,416	2,749
Research and development
Allocation of recognized period cost
Stock-based compensation expense for employee awards	1,651	945	2,935	1,853
General and administrative
Allocation of recognized period cost
Stock-based compensation expense for employee awards	$ 1,307	$ 432	$ 2,397	$ 862

Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

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