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Stock-Based Compensation (Details 3) (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2013	Mar. 31, 2012
Allocation of recognized period cost
Stock-based compensation expense for employee awards	$ 2,374	$ 1,339
Stock-based compensation expense for non-employee awards	12
Total stock-based compensation expense	2,386	1,339
Research and development
Allocation of recognized period cost
Stock-based compensation expense for employee awards	1,284	909
General and administrative
Allocation of recognized period cost
Stock-based compensation expense for employee awards	$ 1,090	$ 430

Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

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