Accounts Payable, Accrued Expenses and Other (Details) (USD $) In Thousands, unless otherwise specified	Mar. 31, 2013	Dec. 31, 2012
Accounts payable, accrued expenses and other
Accounts payable	$ 6,459	$ 283
Accrued goods and services	19,335	17,615
Accrued payroll and related benefits	4,245	5,853
Accrued interest	390	306
Accrued dividends payable	28	28
Total accounts payable, accrued expenses, and other	31,184	24,936
License and Collaboration Agreements | Sanofi
Accounts payable, accrued expenses and other
Contractual liability	$ 727	$ 851