Accounts Payables, Accrued Expenses and Other (Details) (USD $)	Dec. 31, 2012	Dec. 31, 2011
Accounts payable, accrued expenses and other
Accounts payable	$ 283,000	$ 4,656,000
Accrued goods and services	17,615,000	9,189,000
Accrued payroll and related benefits	5,853,000	3,666,000
Accrued interest	306,000
Accrued dividends payable	28,000
Total accounts payable, accrued expenses, and other	24,936,000	17,511,000
License and Collaboration Agreements | Sanofi
Accounts payable, accrued expenses and other
Contractual liability	$ 851,000