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Property and Equipment, Net (Tables)
12 Months Ended
Dec. 31, 2012
Property and Equipment, Net  
Schedule of property and equipment

 

 
  December 31,  
(in thousands)
  2011   2012  

Lab equipment

  $ 11,757   $ 12,616  

IT equipment

    2,204     2,346  

Leasehold improvements

    7,698     8,200  

Furniture and fixtures

    329     330  

Construction in process

    348     1,774  
           

 

    22,336     25,266  

Less: Accumulated depreciation and amortization

    (16,130 )   (18,969 )
           

 

  $ 6,206   $ 6,297