The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100   1,640,579 18,080 SH   SOLE   18,080 0 0
ABBVIE INC COM 00287Y109   3,070,008 12,200 SH   SOLE   12,200 0 0
ABIVAX SA SPONSORED ADS 00370M103   311,828 2,340 SH   SOLE   2,340 0 0
AGOMAB THERAPEUTICS SPONSORED ADS 00860C102   564,630 43,500 SH   SOLE   43,500 0 0
ALNYLAM PHARMACUETCL COM 02043Q107   695,379 2,310 SH   SOLE   2,310 0 0
ALPHATEC HLDGS INC COM NEW 02081G201   1,608,035 185,900 SH   SOLE   0 0 185,900
AMGEN INC COM 031162100   3,335,125 9,210 SH   SOLE   9,210 0 0
ARDELYX INC COM 039697107   624,209 122,394 SH   SOLE   122,394 0 0
ARCUS BIOSCIENCES COM 03969F109   3,418,122 110,870 SH   SOLE   39,870 0 71,000
ARGENX SE SP ADR 04016X101   2,626,517 2,831 SH   SOLE   2,831 0 0
ARRIVENT BIOPHARMA COM 04272N102   2,745,954 79,043 SH   SOLE   28,013 0 51,030
AVALO THERAPEUTICS INC COM NEW 05338F306   2,216,177 119,923 SH   SOLE   31,329 0 88,594
AXSOME THERAPEUTIC COM 05464T104   367,155 1,500 SH   SOLE   1,500 0 0
BEONE MEDICINES LTD SP ADR 07725L102   532,894 1,870 SH   SOLE   1,870 0 0
BIOMARIN PHARMAC COM 09061G101   540,729 9,450 SH   SOLE   9,450 0 0
BIOGEN INC COM 09062X103   399,711 1,850 SH   SOLE   1,850 0 0
BIONTECH SE SP ADR 09075V102   3,895,910 41,869 SH   SOLE   17,664 0 24,205
BOSTON SCIENTIFIC COM 101137107   1,550,564 36,330 SH   SOLE   36,330 0 0
BRIDGEBIO PHARMA COM 10806X102   305,368 4,100 SH   SOLE   4,100 0 0
BRISTOL MYERS SQUIBB COM 110122108   1,218,663 21,150 SH   SOLE   21,150 0 0
CVS HEALTH CORP COM 126650100   1,344,850 13,000 SH   SOLE   13,000 0 0
CENTENE CORP DEL COM 15135B101   770,280 12,000 SH   SOLE   12,000 0 0
COGENT BIOSCIENCES COM 19240Q201   1,034,838 26,740 SH   SOLE   26,740 0 0
CONTINEUM THERAPEUTICS CL A 21217B100   11,925,151 727,587 SH   SOLE   727,587 0 0
ORBUS PHARMACEUTICALS HLDGS COM NEW 21833P301   187,600 20,000 SH   SOLE   20,000 0 0
CYTOKINETICS INC COM NEW 23282W605   1,391,153 16,330 SH   SOLE   16,330 0 0
DANAHER CORP COM 235851102   1,830,726 9,597 SH   SOLE   9,597 0 0
DEFINIUM THERAPEUTICS INC COM SHS 24477V105   3,683,702 78,310 SH   SOLE   31,310 0 47,000
DEXCOM INC COM 252131107   3,418,417 50,756 SH   SOLE   21,906 0 28,850
EDWARDS LIFESCIENCES COM 28176E108   1,341,160 14,826 SH   SOLE   14,826 0 0
ENGENE THERAPEUTICS INC COM 29286X101   37,541 21,700 SH   SOLE   21,700 0 0
GILEAD SCIENCES INC COM 375558103   2,605,131 20,620 SH   SOLE   20,620 0 0
GUARDANT HEALTH INC COM 40131M109   297,059 1,980 SH   SOLE   1,980 0 0
HINGE HEALTH INC CL A 433313103   725,752 8,744 SH   SOLE   8,744 0 0
HUMANA INC INC 444859102   497,299 1,250 SH   SOLE   1,250 0 0
IRHYTHM HOLDINGS INC COM 450056106   3,101,027 26,070 SH   SOLE   6,660 0 19,410
ILLUMINA INC COM 452327109   374,870 2,132 SH   SOLE   2,132 0 0
INCYTE CORPORATION COM 45337C102   266,396 2,350 SH   SOLE   2,350 0 0
INSMED INC COM PAR $.01 457669307   2,475,290 23,216 SH   SOLE   23,216 0 0
INTUITIVE SURGIC INC COM NEW 46120E602   2,326,428 5,850 SH   SOLE   5,850 0 0
IONIS PHARMACEUTICAL COM 462222100   570,888 7,200 SH   SOLE   7,200 0 0
IQVIA HOLDINGS INC COM 46266C105   2,096,051 10,848 SH   SOLE   10,848 0 0
JOHNSON & JOHNSON COM 478160104   4,626,825 18,218 SH   SOLE   18,218 0 0
KURA ONCOLOGY INC COM 50127T109   784,136 71,480 SH   SOLE   71,480 0 0
ELI LILLY & CO COM 532457108   7,621,178 6,354 SH   SOLE   6,354 0 0
MEDPACE HOLDINGS COM 58506Q109   227,724 430 SH   SOLE   430 0 0
MERCK & CO INC COM 58933Y105   2,772,981 21,480 SH   SOLE   21,480 0 0
MINERALYS THERAPEUTICS COM 603170101   392,964 14,565 SH   SOLE   14,565 0 0
MODERNA INC COM 60770K107   304,631 4,350 SH   SOLE   4,350 0 0
NEKTAR THERAPEUTICS COM NEW 640268306   705,849 10,111 SH   SOLE   10,111 0 0
ORIC PHARMACEUTICALS COM 68622P109   254,505 23,500 SH   SOLE   23,500 0 0
ORUKA THERAPEUTICS INC COM 687604108   3,995,903 41,987 SH   SOLE   15,987 0 26,000
PTC THERAPEUTICS INC COM 69366J200   609,328 7,470 SH   SOLE   7,470 0 0
PALISADE BIO INC COM 696389402   183,920 88,000 SH   SOLE   88,000 0 0
PFIZER INC COM 717081103   662,200 27,500 SH   SOLE   27,500 0 0
PRIVIA HEALTH GROUP COM 74276R102   621,019 24,136 SH   SOLE   24,136 0 0
PULSE BIOSCIENCES INC COM 74587B101   1,882,728 67,895 SH   SOLE   0 0 67,895
REGENERON PHARMCTCLS COM 75886F107   1,352,458 2,169 SH   SOLE   2,169 0 0
REVOLUTION MEDICINES COM 76155X100   342,722 1,830 SH   SOLE   1,830 0 0
SHOULDER INNOVATIONS COMMON STOCK 82537J108   8,728,654 430,407 SH   SOLE   430,407 0 0
ARS PHARMACEUTICALS COM 82835W108   239,499 29,900 SH   SOLE   29,900 0 0
STRYKER CORP COM 863667101   2,248,893 7,129 SH   SOLE   7,129 0 0
STRUCTURE THERAPEUTICS SP ADR 86366E106   232,123 4,325 SH   SOLE   4,325 0 0
SUMMIT THERAPEUTICS COM 86627T108   3,208,023 220,180 SH   SOLE   91,805 0 128,375
SYNDAX PHARMACEUTICS COM 87164F105   342,765 15,680 SH   SOLE   15,680 0 0
TARSUS PHARMACEUTICALS COM 87650L103   836,158 13,285 SH   SOLE   13,285 0 0
TECTONIC THERAPEUTIC COM 878972108   2,440,934 71,009 SH   SOLE   24,059 0 46,950
TEMPUS AI INC CL A 88023B103   224,768 3,880 SH   SOLE   3,880 0 0
THERMO FISHER SCIENTIFIC COM 883556102   1,759,926 3,508 SH   SOLE   3,508 0 0
TRANSMEDICS GROUP INC COM 89377M109   1,457,919 21,950 SH   SOLE   0 0 21,950
TREVI THERAPEUTICS COM 89532M101   1,223,365 65,596 SH   SOLE   65,596 0 0
UNITED THERAPEUTICS COM 91307C102   742,307 1,370 SH   SOLE   1,370 0 0
UNITEDHEALTH GRP INC COM 91324P102   5,500,863 13,235 SH   SOLE   13,235 0 0
VERA THERAPEUTICS CL A 92337R101   1,097,337 25,573 SH   SOLE   25,573 0 0
VERTEX PHARMA COM 92532F100   2,698,237 5,432 SH   SOLE   5,432 0 0
CRESCENT BIOPHARMA INC. COM G2545C104   2,183,400 121,300 SH   SOLE   34,700 0 86,600
JAZZ PHARMA PLC SHS USD G50871105   421,698 1,750 SH   SOLE   1,750 0 0
MEDTRONIC PLC SHS G5960L103   876,345 11,100 SH   SOLE   11,100 0 0
ROIVANT SCIENCES LTD SHS G76279101   2,162,329 61,100 SH   SOLE   61,100 0 0
ROYALTY PHARMA PLC SHS CLASS A G7709Q104   403,704 7,200 SH   SOLE   7,200 0 0
ASCENDIS PHARMA A/S ORD SHS K08588103   685,470 2,570 SH   SOLE   2,570 0 0
IMMATICS NV SHS N44445109   2,278,521 224,928 SH   SOLE   66,830 0 158,098