The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ABBOTT LABSCOM0028241009,55179,698SH SOLE 79,69800
ABBVIE INCCOM00287Y1099,90291,500SH SOLE 91,50000
ACCOLADE INCCOM00437E10221,358470,750SH SOLE 105,7500365,000
AGILENT TECHNOLOGIES INCCOM00846U10115,765124,000SH SOLE 00124,000
ALEXION PHARMACEUTICALS INCCOM01535110911,65676,226SH SOLE 5,300070,926
ALIGN TECHNOLOGY INCCOM01625510117,99233,225SH SOLE 7,725025,500
ALIGNMENT HEALTHCARE INCCOM01625V10423,0921,052,987SH SOLE 215,8010837,186
ALIGOS THERAPEUTICS INCCOM01626L10542518,708SH SOLE 18,70800
ALLOVIR INCCOM01981810350221,450SH SOLE 21,45000
ALNYLAM PHARMACEUTICALS INCCOM02043Q10715,495109,746SH SOLE 10,146099,600
AMGEN INCCOM0311621005,30021,303SH SOLE 21,30300
AMICUS THERAPEUTICS INCCOM03152W10917,4551,766,704SH SOLE 57,72501,708,979
ARCUS BIOSCIENCES INCCOM03969F10924,127859,210SH SOLE 95,2500763,960
ARCUTIS BIOTHERAPEUTICS INCCOM03969K10825,428878,948SH SOLE 98,7900780,158
ARENA PHARMACEUTICALS INCCOM NEW04004760722,320321,659SH SOLE 10,6610310,998
ARGENX SESPONSORED ADR04016X1015151,870SH SOLE 1,87000
ARVINAS INCCOM04335A10531,070470,042SH SOLE 48,6630421,379
ASCENDIS PHARMA A/SSPONSORED ADR04351P1014193,250SH SOLE 3,25000
ATEA PHARMACEUTICALS INCCOM04683R10682,6761,338,884SH SOLE 1,338,88400
ATRICURE INCCOM04963C20930,786469,867SH SOLE 30,3620439,505
AVEO PHARMACEUTICALS INCCOM NEW05358830718525,300SH SOLE 25,30000
BEIGENE LTDSPONSORED ADR07725L1022,0195,800SH SOLE 5,80000
BELLUS HEALTH INC NEWCOM NEW07987C2044,8961,274,940SH SOLE 107,85301,167,087
BIOMARIN PHARMACEUTICAL INCCOM09061G1016,60587,472SH SOLE 7,590079,882
BIOGEN INCCOM09062X1033,49212,482SH SOLE 12,48200
BOLT BIOTHERAPEUTICS INCCOM09770210410,532320,010SH SOLE 13,5380306,472
BOSTON SCIENTIFIC CORPCOM1011371073,970102,726SH SOLE 102,72600
BRIDGEBIO PHARMA INCCOM10806X10211,279183,100SH SOLE 7,6000175,500
BRISTOL-MYERS SQUIBB COCOM1101221087,927125,574SH SOLE 125,57400
CIGNA CORP NEWCOM1255231006,35726,297SH SOLE 26,29700
CATALENT INCCOM1488061028,24178,250SH SOLE 0078,250
CENTENE CORP DELCOM15135B10112,608197,275SH SOLE 64,1000133,175
CHECKMATE PHARMACEUTICALS INCOM1628181086,577541,766SH SOLE 541,76600
UNUM THERAPEUTICS INCCOM19240Q20123727,000SH SOLE 27,00000
COOPER COS INCCOM NEW21664840213,32834,700SH SOLE 0034,700
CRYOPORT INCCOM PAR $0.0012290503073,48667,034SH SOLE 67,03400
CYTOSORBENTS CORPCOM NEW23283X2062,367272,660SH SOLE 272,66000
DANAHER CORPORATIONCOM2358511023,77616,775SH SOLE 16,77500
DENALI THERAPEUTICS INCCOM24823R1052284,000SH SOLE 4,00000
DEXCOM INCCOM25213110711,46931,913SH SOLE 8,600023,313
DR REDDYS LABS LTDADR2561352033966,454SH SOLE 6,45400
ESSA PHARMA INCCOM NEW29668H70810,806371,963SH SOLE 20,3700351,593
EVOLENT HEALTH INCCL A30050B10135,2821,746,638SH SOLE 186,10901,560,529
EXACT SCIENCES CORPCOM30063P1057,24855,000SH SOLE 0055,000
EXELIXIS INCCOM30161Q10411,070490,058SH SOLE 120,8780369,180
FATE THERAPEUTICS INCCOM31189P10211,749142,500SH SOLE 00142,500
FINCH THERAPEUTICS GROUP INCCOM31773D1016,299390,000SH SOLE 101,6310288,369
FREELINE THERAPEUTICS HLDGSSPONSORED ADS35655L1078,050654,498SH SOLE 27,5690626,929
GENERATION BIO COCOM37148K10061321,522SH SOLE 21,52200
GENETRON HLDGS LTDADS37186H10023210,800SH SOLE 10,80000
GILEAD SCIENCES INCCOM3755581031,89029,250SH SOLE 29,25000
GUARDANT HEALTH INCCOM40131M10910,89771,386SH SOLE 5,470065,916
HARPOON THERAPEUTICS INCCOM41358P10613,202631,050SH SOLE 128,0930502,957
HOLOGIC INCCOM43644010112,109162,800SH SOLE 00162,800
ILLUMINA INCCOM4523271091,5984,160SH SOLE 4,16000
INCYTE CORPCOM45337C1026678,210SH SOLE 8,21000
INSMED INCCOM PAR $.0145766930712,609370,200SH SOLE 8,7000361,500
INSPIRE MED SYS INCCOM45773010912,52360,500SH SOLE 0060,500
INSTIL BIO INCCOM45783C1019,461377,250SH SOLE 69,6680307,582
INNOVAGE HLDG CORPCOM45784A10412,374479,794SH SOLE 102,8210376,973
INSULET CORPCOM45784P10112,35647,354SH SOLE 0047,354
INVITAE CORPCOM46185L10321,923573,759SH SOLE 13,6010560,158
JOHNSON & JOHNSONCOM47816010411,91572,500SH SOLE 72,50000
LABORATORY CORP AMER HLDGSCOM NEW50540R40920,09978,812SH SOLE 0078,812
LEGEND BIOTECH CORPSPONSORED ADS52490G10229910,300SH SOLE 10,30000
LILLY ELI & COCOM5324571088,72746,715SH SOLE 46,71500
MEI PHARMA INCCOM NEW55279B2026,7291,961,667SH SOLE 693,98001,267,687
MIRATI THERAPEUTICSMIRATI THERAPEUTICS INC60468T10513,54779,081SH SOLE 2,431076,650
MODERNA INCCOM60770K1072,07615,850SH SOLE 15,85000
MOLECULAR TEMPLATES INCCOM6085501097,780616,450SH SOLE 223,8050392,645
MOLINA HEALTHCARE INCCOM60855R1008,85937,897SH SOLE 0037,897
NATERA INCCOM63230710413,083128,850SH SOLE 00128,850
NKARTA INCCOM65487U1085,562169,050SH SOLE 14,0500155,000
NOVAVAX INCCOM NEW67000240134,666191,200SH SOLE 6,0000185,200
NUCANA PLCSPONSORED ADR67022C1065,5631,114,801SH SOLE 450,0550664,746
OAK STR HEALTH INCCOM67181A10719,062351,250SH SOLE 38,9240312,326
OLEMA PHARMACEUTICALS INCCOM68062P10642812,900SH SOLE 12,90000
OLINK HLDG ABSPONSORED ADS68071010015,307425,198SH SOLE 71,2050353,993
ONCORUS INCCOM68236R1034,663335,000SH SOLE 169,9860165,014
PRA HEALTH SCIENCES INCCOM69354M10811,22473,200SH SOLE 8,400064,800
PPD INCCOM69355F10232,260852,525SH SOLE 70,0890782,436
PTC THERAPEUTICS INCCOM69366J20023,908504,928SH SOLE 15,6750489,253
PERSONALIS INCCOM71535D1062,966120,500SH SOLE 120,50000
PFIZER INCCOM7170811033,16787,400SH SOLE 87,40000
PULMONX CORPCOM7458481019,281202,900SH SOLE 00202,900
QUANTERIX CORPCOM74766Q10114,248243,689SH SOLE 6,6810237,008
R1 RCM INCCOM74939710526,3531,067,768SH SOLE 54,62301,013,145
REGENERON PHARMACEUTICALSCOM75886F1072,1864,620SH SOLE 4,62000
REPLIGEN CORPCOM75991610924,242124,693SH SOLE 00124,693
REPARE THERAPEUTICS INCCOM76027310230710,000SH SOLE 10,00000
RESMED INCCOM76115210714,76676,105SH SOLE 0076,105
ROCKET PHARMACEUTICALS INCCOM77313F10619,873447,885SH SOLE 10,4850437,400
SEAGEN INCCOM81181C1047,27752,406SH SOLE 6,730045,676
SOTERA HEALTH COCOM83601L1022,25690,368SH SOLE 90,36800
STRYKER CORPCOM8636671013,33713,700SH SOLE 13,70000
TALIS BIOMEDICAL CORPCOM87424L1085,205405,094SH SOLE 24,8750380,219
TANDEM DIABETES CARE INCCOM NEW8753722033,09835,100SH SOLE 35,10000
TELADOC HEALTH INCCOM87918A10522,667124,713SH SOLE 39,975084,738
TELEFLEX INCORPORATEDCOM87936910633,16179,818SH SOLE 0079,818
TG THERAPEUTICS INCCOM88322Q10824,758513,649SH SOLE 10,9490502,700
THERMO FISHER SCIENTIFIC INCCOM8835561024,74610,400SH SOLE 10,40000
TURNING POINT THERAPEUTICS ICOM90041T10824,393257,879SH SOLE 31,7480226,131
ULTRAGENYX PHARMACEUTICAL INCOM90400D10812,775112,200SH SOLE 00112,200
UNITEDHEALTH GROUP INCCOM91324P1028,79923,650SH SOLE 23,65000
VERTEX PHARMACEUTICALS INCCOM92532F1002,43311,321SH SOLE 11,32100
VIRACTA THERAPEUTICS INCCOM92765F1085,990647,556SH SOLE 54,6820592,874
VOR BIOPHARMA INCCOM92903310823,070535,259SH SOLE 19,3390515,920
ZAI LAB LTDADR98887Q1047875,900SH SOLE 5,90000
ZIMMER BIOMET HOLDINGS INCCOM98956P10219,290120,500SH SOLE 00120,500
HORIZON THERAPEUTICS PUB LSHSG4618810113,113142,475SH SOLE 52,475090,000
MEDTRONIC PLCSHSG5960L1036,20252,501SH SOLE 52,50100
ORTHO CLINICAL DIAGNOSTICS HORD SHSG6829J10733,3901,730,500SH SOLE 137,23001,593,270
CRISPR THERAPEUTICS AGNAMEN AKTH171821083983,270SH SOLE 3,27000