The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COMMON 002824100 21,853 382,909 SH   SOLE   382,909 0 0
ABBVIE INC COMMON 00287Y109 8,249 85,298 SH   SOLE   85,298 0 0
ABIOMED INC COMMON 003654100 15,887 84,774 SH   SOLE   31,275 0 53,499
ACADIA HEALTHCARE COMMON 00404A109 4,131 126,602 SH   SOLE   0 0 126,602
ACADIA PHARMACEUTICALS COMMON 004225108 34,076 1,131,722 SH   SOLE   542,527 0 589,195
ACCELERON PHARMA COMMON 00434H108 30,232 712,356 SH   SOLE   372,417 0 339,939
ACCURAY INC COMMON 004397105 2,560 595,447 SH   SOLE   900 0 594,547
AERIE PHARMACEUTICALS COMMON 00771V108 22,036 368,797 SH   SOLE   169,697 0 199,100
AGIOS PHARMACEUTICALS COMMON 00847X104 2,733 47,799 SH   SOLE   0 0 47,799
ALBIREO PHARMA INC COMMON 01345P106 6,216 242,803 SH   SOLE   125,014 0 117,789
AMICUS THERAPEUTICS COMMON 03152W109 41,023 2,850,769 SH   SOLE   1,529,595 0 1,321,174
APELLIS PHARMACEUTIC COMMON 03753U106 38,033 1,752,655 SH   SOLE   1,467,755 0 284,900
BIOMARIN PHARMAC INC COMMON 09061G101 23,051 258,503 SH   SOLE   258,503 0 0
CELGENE CORP COMMON 151020104 24,194 231,830 SH   SOLE   231,830 0 0
CIGNA CORP COMMON 125509109 13,732 67,615 SH   SOLE   67,615 0 0
CLEMENTIA PHARMACEUTICALS COMMON 185575107 1,429 75,313 SH   SOLE   75,313 0 0
CLOVIS ONCOLOGY COMMON 189464100 12,417 182,600 SH   SOLE   51,400 0 131,200
COLLEGIUM PHARMACEUTICAL COMMON 19459J104 26,340 1,426,862 SH   SOLE   919,394 0 507,468
DBV TECHNOLOGIES SPNS AD 23306J101 1,483 60,298 SH   SOLE   60,298 0 0
DR REDDYS LABS LTD ADR 256135203 958 25,496 SH   SOLE   25,496 0 0
EDWARDS LIFESCIENCE COMMON 28176E108 17,819 158,100 SH   SOLE   158,100 0 0
ELI LILLY & CO COMMON 532457108 13,868 164,200 SH   SOLE   164,200 0 0
ESPERION THERAPEUTICS COMMON 29664W105 1,536 23,333 SH   SOLE   23,333 0 0
EVOLENT HEALTH INC COMMON 30050B101 6,051 491,982 SH   SOLE   1,030 0 490,952
EXACT SCIENCES CORP COMMON 30063P105 10,111 192,450 SH   SOLE   40,350 0 152,100
GLOBAL BLOOD THERAPEUTICS COMMON 37890U108 17,384 441,768 SH   SOLE   222,715 0 219,053
HILL-ROM HLDS INC COMMON 431475102 5,854 69,450 SH   SOLE   50 0 69,400
INCYTE CORPORATION COMMON 45337C102 3,688 38,945 SH   SOLE   38,945 0 0
INSMED INC COMMON 457669307 2,812 90,199 SH   SOLE   90,199 0 0
INSULET CORP COMMON 45784P101 6,521 94,509 SH   SOLE   0 0 94,509
INTEC PHARMA LTD JERUSALEM SHS M53644106 1,828 355,000 SH   SOLE   355,000 0 0
INTEGRA LIFESCIENCE COMMON 457985208 5,896 123,198 SH   SOLE   0 0 123,198
IRHYTHM TECHNOLOGIES COMMON 450056106 10,919 194,800 SH   SOLE   100 0 194,700
JOHNSON & JOHNSON COMMON 478160104 29,949 214,349 SH   SOLE   214,349 0 0
K2M GROUP HOLDINGS COMMON 48273J107 20,959 1,164,412 SH   SOLE   580,612 0 583,800
LA JOLLA PHARMACEUTICAL COMMON 503459604 27,491 854,301 SH   SOLE   530,377 0 323,924
LOXO ONCOLOGY INC COMMON 548862101 12,811 152,185 SH   SOLE   24,303 0 127,882
MADRIGAL PHARMACEUTICALS COMMON 558868105 3,382 36,850 SH   SOLE   17,763 0 19,087
MASIMO CORP COMMON 574795100 6,173 72,800 SH   SOLE   0 0 72,800
MEDTRONIC PLC SHS G5960L103 14,665 181,610 SH   SOLE   181,610 0 0
MERCK & CO INC COMMON 58933Y105 6,105 108,501 SH   SOLE   108,501 0 0
MOLINA HEALTHCARE COMMON 60855R100 4,007 52,260 SH   SOLE   60 0 52,200
MOMENTA PHARMACEUTICALS COMMON 60877T100 6,979 500,298 SH   SOLE   307,399 0 192,899
NEKTAR THERAPEUTICS COMMON 640268108 7,036 117,815 SH   SOLE   70,615 0 47,200
NEUROCRINE BIOSCIENCES COMMON 64125C109 11,041 142,302 SH   SOLE   32,495 0 109,807
NOVARTIS AG SPNS AD 66987V109 31,527 375,496 SH   SOLE   375,496 0 0
OBSEVA SA COMMON H5861P103 2,063 211,407 SH   SOLE   211,407 0 0
PFIZER INC COMMON 717081103 31,514 870,074 SH   SOLE   870,074 0 0
PORTOLA PHARMACEUTICALS COMMON 737010108 26,113 536,414 SH   SOLE   286,472 0 249,942
PROTEOSTASIS THERAPEUTICS COMMON 74373B109 1,749 300,000 SH   SOLE   300,000 0 0
PROTHENA CORP PLC SHS G72800108 6,901 184,063 SH   SOLE   90,863 0 93,200
PTC THERAPEUTICS COMMON 69366J200 6,216 372,634 SH   SOLE   132,935 0 239,699
PUMA BIOTECHNOLOGY COMMON 74587V107 1,488 15,050 SH   SOLE   15,050 0 0
REGENERON PHARMACEUTICALS COMMON 75886F107 14,781 39,316 SH   SOLE   39,316 0 0
SAGE THERAPEUTICS COMMON 78667J108 2,833 17,200 SH   SOLE   17,200 0 0
SAREPTA THERAPEUTICS COMMON 803607100 13,298 238,999 SH   SOLE   93,099 0 145,900
SAVARA INC COMMON 805111101 2,374 160,000 SH   SOLE   160,000 0 0
SIERRA ONCOLOGY INC COMMON 82640U107 752 201,660 SH   SOLE   201,660 0 0
SPARK THERAPEUTICS COMMON 84652J103 4,288 83,390 SH   SOLE   35,291 0 48,099
SPRING BK PHARMACEUTICALS COMMON 849431101 1,658 123,383 SH   SOLE   123,383 0 0
TELADOC INC COMMON 87918A105 23,755 681,628 SH   SOLE   373,120 0 308,508
TESARO INC COMMON 881569107 3,033 36,600 SH   SOLE   36,600 0 0
UNITEDHEALTH GROUP INC COMMON 91324P102 18,277 82,904 SH   SOLE   82,904 0 0
VERTEX PHARMACEUTICALS COMMON 92532F100 5,502 36,715 SH   SOLE   36,715 0 0
VIEWRAY INC COMMON 92672L107 8,772 947,306 SH   SOLE   467,811 0 479,495
WRIGHT MED GROUP N V ORD EUR N96617118 6,837 307,972 SH   SOLE   300 0 307,672
ZAI LAB LTD ADR 98887Q104 1,053 49,584 SH   SOLE   49,584 0 0