X0306 4 2019-05-29 0 0000831547 SPECTRUM PHARMACEUTICALS INC SPPI 0001273213 MAIDA ANTHONY E III 11500 S. EASTERN AVE. SUITE 240 HENDERSON NV 89052 1 0 0 0 Common Stock, $0.001 par value 2019-05-29 4 M 0 50000 6.09 A 72250 D Common Stock, $0.001 par value 2019-05-29 4 S 0 42643 7.747 D 29607 D Stock Option Exercise (Right to Buy) 6.09 2019-05-29 4 M 0 50000 0.00 D 2012-06-26 2019-06-26 Common Stock 50000 0 D This transaction represents an open market sale of a portion of the expiring stock options exercised on this Form 4 to satisfy the Reporting Person's payment of the exercise price and the taxes associated with such exercise. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $7.695 to $7.82, inclusive. The reporting person undertakes to provide to Spectrum Pharmaceuticals, Inc., any security holder of Spectrum Pharmaceuticals, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. /s/ Kurt A. Gustafson, attorney-in-fact for Anthony E. Maida 2019-05-31