X0303 4 2010-10-21 0 0000895421 MORGAN STANLEY MS 0001272147 MACK JOHN J C/O MORGAN STANLEY 1585 BROADWAY NEW YORK NY 10036 1 1 0 0 Chairman of the Board Common Stock 2010-10-21 4 J 0 28900 24.85 A 2249387.243 D Common Stock 875.369 I By 401(k) Plan Common Stock 356800 I By Grantor Retained Annuity Trust On October 21, 2010, the Reporting Person substituted assets of equal value into a grantor retained annuity trust in exchange for 28,900 shares of Common Stock. Since the Reporting Person's last report, 107,500 shares of Common Stock previously reported as indirectly beneficially owned by grantor retained annuity trust were transferred back to the Reporting Person in satisfaction of an annuity payment. /s/ Charlene R. Herzer, Agent and Attorney-in-Fact 2010-10-22