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Product Revenue, Net (Tables)
9 Months Ended
Sep. 30, 2019
Product Revenue, Net [Abstract]  
Product Revenues

The table below summarizes consolidated product revenue, net by region:

Three Months Ended September 30, 

Nine Months Ended September 30, 

    

2019

    

2018

    

2019

    

2018

(in thousands)

(in thousands)

Product revenue, net:

 

  

 

  

 

  

 

  

U.S.

$

45,232

$

36,684

$

133,914

$

99,697

ex-U.S.

 

16,313

 

9,897

 

45,372

 

25,211

Total product revenue, net

$

61,545

$

46,581

$

179,286

$

124,908