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Product Revenue, Net (Tables)
6 Months Ended
Jun. 30, 2019
Product Revenue, Net [Abstract]  
Product Revenues

The table below summarizes consolidated product revenue, net by region:

Three Months Ended June 30, 

Six Months Ended June 30, 

    

2019

    

2018

    

2019

    

2018

(in thousands)

(in thousands)

Product revenue, net:

 

  

 

  

 

  

 

  

U.S.

$

50,691

$

34,500

$

88,682

$

63,013

ex-U.S.

 

15,203

 

8,669

 

29,059

 

15,314

Total product revenue, net

$

65,894

$

43,169

$

117,741

$

78,327