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Consolidated Statements of Changes in Stockholders' Equity (USD $)
Series A Preferred Stock [Member]
Series B Preferred Stock [Member]
Series C Preferred Stock [Member]
Common Stock [Member]
Additional Paid-In Capital [Member]
Retained Earnings [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Total
Balance at Sep. 03, 2002 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0
Balance (in shares) at Sep. 03, 2002 0 0 0 0        
Initial capitalization (founders) - September 10, 2002 0 0 0 949 26,468 0 0 27,417
Initial capitalization (founders) - September 10, 2002 (in shares) 0 0 0 949,035        
Subscription - November 1, 2002 0 0 0 61 1,689 0 0 1,750
Subscription - November 1, 2002 (in shares) 0 0 0 60,576        
Subscription - October 1, 2003 0 0 0 112 3,138 0 0 3,250
Subscription - October 1, 2003 (in shares) 0 0 0 112,498        
Repurchase of founders shares - October 27, 2003 0 0 0 (551) (15,366) 0 0 (15,917)
Repurchase of founders shares - October 27, 2003 (in shares) 0 0 0 (550,960)        
Private placement - from October 27, 2003 through May 5, 2004 0 0 0 392 2,832,088 0 0 2,832,480
Private placement - from October 27, 2003 through May 5, 2004 (in shares) 0 0 0 392,163        
Private placement - November 8, 2005 0 0 0 52 374,948 0 0 375,000
Private placement - November 8, 2005 (in shares) 0 0 0 51,922        
Private placement - May 8, 2006 0 0 0 2,087 20,497,913 0 0 20,500,000
Private placement - May 8, 2006 (in shares) 0 0 0 2,087,091        
Conversion of promissory notes - May 8, 2006 0 0 0 161 1,341,088 0 0 1,341,249
Conversion of promissory notes - May 8, 2006 (in shares) 0 0 0 160,637        
Commissions, legal, and other costs for private placement 0 0 0 0 (1,500,138) 0 0 (1,500,138)
Stock-based compensation:                
Directors and employees 0 0 0 0 604,372 0 0 604,372
Consultants 0 0 0 0 494,685 0 0 494,685
Exercise of stock options 0 0 0 6 17,699 0 0 17,705
Exercise of stock options (in shares) 0 0 0 6,129        
Exercise of warrants 0 0 0 52 374,948 0 0 375,000
Exercise of warrants (in shares) 0 0 0 51,922        
Other comprehensive Income (loss) 0 0 0 0 0 0 84,978 84,978
Net loss 0 0 0 0 0 (18,656,010) 0 (18,656,010)
Balance at Dec. 31, 2007 0 0 0 3,321 25,053,532 (18,656,010) 84,978 6,485,821
Balance (in shares) at Dec. 31, 2007 0 0 0 3,321,013        
Private placement May 23, 2008 13,889 0 0 0 24,986,111 0 0 25,000,000
Private placement May 23, 2008 (in shares) 13,888,889              
Commissions, legal, and other costs for private placement 0 0 0 0 (749,075) 0 0 (749,075)
Stock-based compensation:                
Directors and employees 0 0 0 0 682,025 0 0 682,025
Consultants 0 0 0 0 127,359 0 0 127,359
Other comprehensive Income (loss) 0 0 0 0 0 0 (155,784) (155,784)
Net loss 0 0 0 0 0 (13,704,870) 0 (13,704,870)
Balance at Dec. 31, 2008 13,889 0 0 3,321 50,099,952 (32,360,880) (70,806) 17,685,476
Balance (in shares) at Dec. 31, 2008 13,888,889 0 0 3,321,013        
Stock-based compensation:                
Directors and employees 0 0 0 0 908,375 0 0 908,375
Consultants 0 0 0 0 53,425 0 0 53,425
Exercise of stock options 0 0 0 9 24,991 0 0 25,000
Exercise of stock options (in shares) 0 0 0 8,653        
Cumulative effect of accounting adjustment 0 0 0 0 (2,187,680) 0 0 (2,187,680)
Other comprehensive Income (loss) 0 0 0 0 0 0 (7,314) (7,314)
Net loss 0 0 0 0 0 (14,354,522) 0 (14,354,522)
Balance at Dec. 31, 2009 13,889 0 0 3,330 48,899,063 (46,715,402) (78,120) 2,122,760
Balance (in shares) at Dec. 31, 2009 13,888,889 0 0 3,329,666        
Commissions, legal, and other costs for private placement 0 0 0 0 (111,704) 0 0 (111,704)
Stock-based compensation:                
Directors and employees 0 0 0 0 1,604,117 0 0 1,604,117
Consultants 0 0 0 0 88,768 0 0 88,768
Private placement January 20, 2010 0 13,889 0 0 19,787,894 0 0 19,801,783
Private placement January 20, 2010 (in shares) 0 13,888,889 0 0        
Other comprehensive Income (loss) 0 0 0 0 0 0 (100,035) (100,035)
Net loss 0 0 0 0 0 (15,087,223) 0 (15,087,223)
Balance at Dec. 31, 2010 13,889 13,889 0 3,330 70,268,138 (61,802,625) (178,155) 8,318,466
Balance (in shares) at Dec. 31, 2010 13,888,889 13,888,889 0 3,329,666        
Stock-based compensation:                
Directors and employees 0 0 0 0 1,779,785 0 0 1,779,785
Consultants 0 0 0 0 85,970 0 0 85,970
Other comprehensive Income (loss) 0 0 0 0 0 0 (6,345) (6,345)
Net loss 0 0 0 0 0 (12,737,654) 0 (12,737,654)
Balance at Dec. 31, 2011 13,889 13,889 0 3,330 72,133,893 (74,540,279) (184,500) (2,559,778)
Balance (in shares) at Dec. 31, 2011 13,888,889 13,888,889 0 3,329,666        
Stock-based compensation:                
Directors and employees 0 0 0 0 2,436,430 0 0 2,436,430
Consultants 0 0 0 0 912,559 0 0 912,559
Private placement - August 9, 2012 0 0 15,000 0 29,715,000 0 0 29,730,000
Private placement - August 9, 2012 (in shares) 0 0 15,000,000 0        
Preferred shares converted to common stock (13,889) (13,889) (15,000) 7,404 35,374 0 0 0
Preferred shares converted to common stock (in shares) (13,888,889) (13,888,889) (15,000,000) 7,403,817        
Issuance of common stock from initial public offering, net of underwriting fees and issuance costs 0 0 0 5,750 78,764,246 0 0 78,769,996
Issuance of common stock from initial public offering, net of underwriting fees and issuance costs (in shares) 0 0 0 5,750,000        
Warrants converted to common stock 0 0 0 43 1,018,172 0 0 1,018,215
Warrants converted to common stock (in shares) 0 0 0 43,402        
Reclassification of warrants from equity to liabilities 0 0 0 0 (915,535) 0 0 (915,535)
Other comprehensive Income (loss) 0 0 0 0 0 0 163,049 163,049
Net loss 0 0 0 0 0 (43,643,071) 0 (43,643,071)
Balance at Dec. 31, 2012 $ 0 $ 0 $ 0 $ 16,527 $ 184,100,139 $ (118,183,350) $ (21,451) $ 65,911,865
Balance (in shares) at Dec. 31, 2012 0 0 0 16,526,885