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Consolidated Statements of Operations and Comprehensive Loss (USD $)
12 Months Ended 124 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2012
Licensing revenue $ 2,446,105 $ 1,805,130 $ 0 $ 4,251,235
Costs and expenses:        
Research and development 16,182,564 11,426,155 12,709,590 71,434,691
General and administrative 5,177,129 4,209,429 3,643,623 29,598,082
Total costs and expenses 21,359,693 15,635,584 16,353,213 101,032,773
Other income (expense):        
Revaluation of warrants (24,625,598) 1,044,826 672,477 (23,075,576)
Foreign currency loss on liquidation (191,733) 0 0 (191,733)
Other income, net 87,848 47,974 104,554 1,376,538
QTDP Grant 0 0 488,959 488,959
Total Other income (expense) (24,729,483) 1,092,800 1,265,990 (21,401,812)
Net loss (43,643,071) (12,737,654) (15,087,223) (118,183,350)
Dividends on preferred stock, not declared (2,630,435) (3,000,000) (2,901,370) (10,944,134)
Net loss attributable to common stockholders (46,273,506) (15,737,654) (17,988,593) (129,127,484)
Net loss per share, basic and diluted (in dollars per share) $ (7.36) $ (4.73) $ (5.40)  
Weighted average shares outstanding, basic and diluted (in shares) 6,283,238 3,329,666 3,329,666  
Other comprehensive gain/(loss):        
Unrealized (loss) on investment securities (21,451)     (21,451)
Foreign currency translation adjustments 184,500 (6,345) (100,035) 0
Total comprehensive loss $ (43,480,022) $ (12,743,999) $ (15,187,258) $ (118,204,801)