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Fair Value Measurements - Summary of Changes in Estimated Fair Value of Embedded Derivative Liabilities Measured on Recurring Basis (Detail)
$ in Thousands
12 Months Ended
Dec. 31, 2019
USD ($)
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]  
Beginning balance $ 11,698
Net change in the fair value 2,893
Addition of derivative related to 2019 Secured Term Loan 4,300
Settlement of Lonza award (15,025)
Ending balance 3,866
Embedded derivative liabilities  
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]  
Beginning balance 2,497
Net change in the fair value (2,931)
Addition of derivative related to 2019 Secured Term Loan 4,300
Settlement of Lonza award 0
Ending balance 3,866
Lonza award  
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]  
Beginning balance 9,201
Net change in the fair value 5,824
Addition of derivative related to 2019 Secured Term Loan 0
Settlement of Lonza award (15,025)
Ending balance $ 0