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Long Term Obligations - Schedule of Payment Obligations (Detail) - USD ($)
$ in Thousands
Sep. 30, 2019
Dec. 31, 2018
Debt Instrument [Line Items]    
Non-current portion of notes payable $ 41,928 $ 48,298
Non-current portion of long term royalty-based debt 57,269 0
Royalty Based Debt | HealthCare Royalty Partners and its Affiliates (“HCR”)    
Debt Instrument [Line Items]    
Less: interests to be accreted in future periods (109,060) (125,851)
Less: payments made (6,006) (816)
Less: current portion of royalties (18,302) (8,627)
Total repayment obligations 290,550 290,550
Carrying value of long term royalty-based debt 175,484 163,883
Non-current portion of long term royalty-based debt 157,182 155,256
Bristol-Myers Squibb Company ("BMS") and Pfizer Inc. ("Pfizer") | Promissory Notes    
Debt Instrument [Line Items]    
Total repayment obligations 62,500 62,500
Less: interests to be accreted in future periods (6,191) (8,643)
Less: payments made (3,564) (497)
Carrying value of notes payable 52,745 53,360
Less: current portion of royalties (10,817) (5,062)
Non-current portion of notes payable $ 41,928 $ 48,298