Summary of Significant Accounting Policies - Additional Information (Detail)		3 Months Ended			9 Months Ended
	Jan. 01, 2019 USD ($)	Sep. 30, 2019 USD ($) customer	Sep. 30, 2018 customer	Mar. 31, 2018 USD ($)	Sep. 30, 2019 USD ($) customer	Sep. 30, 2018 customer
Summary Of Significant Accounting Policies [Line Items]
Operating leases, right-of-use assets		$ 11,836,000			$ 11,836,000
Operating leases, liabilities		$ 13,030,000			$ 13,030,000
Cumulative impact on accumulated deficit				$ 29,037,000
Accounting Standards Update (“ASU”) No. 2016-02
Summary Of Significant Accounting Policies [Line Items]
Operating leases, right-of-use assets	$ 2,100,000
Operating leases, liabilities	3,300,000
Cumulative impact on accumulated deficit	$ 0
Maximum
Summary Of Significant Accounting Policies [Line Items]
Leasing arrangements terms		1 year			1 year
Andexxa Specialty Distributor | Customer Concentration Risk | Sales Revenue, Net
Summary Of Significant Accounting Policies [Line Items]
Number of customers representing more than ten percent of revenue | customer		4	3		4	3
Andexxa Specialty Distributor | Customer Concentration Risk | Sales Revenue, Net | Minimum
Summary Of Significant Accounting Policies [Line Items]
Concentration risk percentage		10.00%	10.00%		10.00%	10.00%
Collaboration Revenue Customers | Customer Concentration Risk | Sales Revenue, Net
Summary Of Significant Accounting Policies [Line Items]
Number of customers representing more than ten percent of revenue | customer		0	2		0	2
Collaboration Revenue Customers | Customer Concentration Risk | Sales Revenue, Net | Minimum
Summary Of Significant Accounting Policies [Line Items]
Concentration risk percentage		10.00%	10.00%		10.00%	10.00%