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Asset Acquisition and License Agreements - Additional Information (Detail) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Dec. 31, 2015
Jun. 30, 2019
Jun. 30, 2019
Asset Acquisition [Line Items]      
Impairment charge of intangible asset     $ 3,151
SRX Cardio      
Asset Acquisition [Line Items]      
Variable interest entity, Upfront payment $ 500    
Gain on de-recognition of contingent milestone payable   $ 2,300 2,300
SRX Cardio | In-process Research and Development      
Asset Acquisition [Line Items]      
Impairment charge of intangible asset   $ 3,200 $ 3,200