Summary of Significant Accounting Policies - Additional Information (Detail)		3 Months Ended			6 Months Ended
	Jan. 01, 2019 USD ($)	Jun. 30, 2019 USD ($) Customer	Jun. 30, 2018 Customer	Mar. 31, 2018 USD ($)	Jun. 30, 2019 USD ($) Customer	Jun. 30, 2018 Customer
Summary Of Significant Accounting Policies [Line Items]
Operating leases, right-of-use assets		$ 12,316,000			$ 12,316,000
Operating leases, liabilities		$ 13,208,000			$ 13,208,000
Cumulative impact on accumulated deficit				$ 29,037,000
Accounting Standards Update (“ASU”) No. 2016-02
Summary Of Significant Accounting Policies [Line Items]
Operating leases, right-of-use assets	$ 2,100
Operating leases, liabilities	3,300
Cumulative impact on accumulated deficit	$ 0
Maximum
Summary Of Significant Accounting Policies [Line Items]
Leasing arrangements terms		1 year			1 year
Andexxa Specialty Distributor | Customer Concentration Risk | Sales Revenue, Net
Summary Of Significant Accounting Policies [Line Items]
Number of customers representing more than ten percent of revenue | Customer		4	0		4	0
Andexxa Specialty Distributor | Customer Concentration Risk | Sales Revenue, Net | Minimum
Summary Of Significant Accounting Policies [Line Items]
Concentration risk percentage		10.00%	10.00%		10.00%	10.00%
Collaboration Revenue Customers | Customer Concentration Risk | Sales Revenue, Net
Summary Of Significant Accounting Policies [Line Items]
Number of customers representing more than ten percent of revenue | Customer		0	1		0	2
Collaboration Revenue Customers | Customer Concentration Risk | Sales Revenue, Net | Minimum
Summary Of Significant Accounting Policies [Line Items]
Concentration risk percentage		10.00%	10.00%		10.00%	10.00%