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Summary of Significant Accounting Policies - Schedule of Cash as Reported in Condensed Consolidated Statements of Cash Flows (Detail) - USD ($)
$ in Thousands
Jun. 30, 2019
Dec. 31, 2018
Jun. 30, 2018
Dec. 31, 2017
Restricted Cash And Cash Equivalents Items [Line Items]        
Cash and cash equivalents $ 185,385 $ 138,951 $ 173,052 $ 181,568
Restricted cash 2,280 1,062    
Total cash balance in condensed consolidated statements of cash flows 187,665 140,013 173,082 181,741
SRX Cardio        
Restricted Cash And Cash Equivalents Items [Line Items]        
Restricted cash   30 $ 30 $ 173
Royalty Payments | HealthCare Royalty Partners and its Affiliates (“HCR”)        
Restricted Cash And Cash Equivalents Items [Line Items]        
Restricted cash $ 2,280 $ 1,032