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Accrued and Other Liabilities (Detail) - USD ($)
$ in Thousands
Jun. 30, 2018
Dec. 31, 2017
Payables And Accruals [Abstract]    
Commercial related $ 3,639 $ 1,694
Legal and accounting fees 727 256
Deferred rent 919 879
Current portion of long term obligation to collaborator 451  
Other 1,720 723
Total accrued and other liabilities $ 7,456 $ 3,552