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Comparison of Reported Condensed Consolidated Statement of Operations Under New Guidance (Detail) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Revenues:    
Collaboration and license revenue $ 6,038 $ 5,128
Operating expenses:    
Research and development 60,067 30,645
Loss from operations (85,300) (40,538)
Net loss (84,510) (41,764)
Net loss attributable to Portola $ (84,178) $ (41,719)
Basic and diluted $ (1.28) $ (0.74)
Balances without the adoption of ASC 606 | Accounting Standards Update 2014-09    
Revenues:    
Collaboration and license revenue $ 6,354  
Operating expenses:    
Research and development 59,345  
Loss from operations (84,262)  
Net loss (83,472)  
Net loss attributable to Portola $ (83,140)  
Basic and diluted $ (1.27)  
Effect of change | Accounting Standards Update 2014-09    
Revenues:    
Collaboration and license revenue $ (316)  
Operating expenses:    
Research and development 722  
Loss from operations (1,038)  
Net loss (1,038)  
Net loss attributable to Portola $ (1,038)  
Basic and diluted $ (0.01)