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Stock Based Compensation (Tables)

9 Months Ended

Sep. 30, 2017

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

The following table summarizes stock option activity under our 2013 Plan and 2017 Plan and related information during the nine months ended September 30, 2017:

	Shares
	Subject to			Weighted-
	Outstanding			Average Exercise
	Options			Price Per Share
Balance at December 31, 2016		5,817,116		$	25.26
Options granted		1,813,300			38.68
Options exercised		(1,008,791	)		15.37
Options canceled		(200,522	)		35.48
Balance at September 30, 2017		6,421,103		$	30.28

Summary of PSO Activity

The following table summarizes PSO activity under our 2013 Plan and related information during the nine months ended September 30, 2016:

	Shares
	Subject to			Weighted-
	Outstanding			Average Exercise
	Options			Price Per Share
Balance at December 31, 2016		180,752		$	23.76
Options granted		—			—
Options exercised		(4,635	)		—
Options canceled		—			—
Balance at September 30, 2017		176,117		$	23.76

Summary of RSU Activity

The following table summarizes RSU activity, under our 2013 Plan and related information:

	Shares
	Subject to			Weighted-
	Outstanding			Average grant date
	RSUs			fair value per share
Balance at December 31, 2016		546,507		$	28.38
RSUs granted		338,800			26.80
RSUs released		(211,882	)		28.26
RSUs canceled		(35,653	)		27.25
Balance at September 30, 2017		637,772		$	27.65

Summary of PSU Activity

The following table summarizes PSU activity, under our 2013 Plan and related information:

	Shares
	Subject to			Weighted-
	Outstanding			Average grant date
	PSUs			fair value per share
Balance at December 31, 2016		285,866		$	29.24
PSUs granted		143,750			25.54
PSUs released		(60,374	)		35.97
PSUs canceled		(52,281	)		33.76
Balance at September 30, 2017		316,961		$	25.53

Classification of Stock-Based Compensation Expense

The table below sets forth the functional classification of stock-based compensation expense, for the periods presented (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2017		2016		2017		2016
Research and development	$	4,155	$	3,465	$	14,974	$	9,561
Selling, general and administrative		5,960		4,307		17,431		12,903
Total stock-based compensation	$	10,115	$	7,772	$	32,405	$	22,464