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Stock Based Compensation (Tables)

6 Months Ended

Jun. 30, 2017

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

The following table summarizes stock option activity under our 2013 Plan and related information during the six months ended June 30, 2017:

	Shares
	Subject to			Weighted-
	Outstanding			Average Exercise
	Options			Price Per Share
Balance at December 31, 2016		5,817,116		$	25.26
Options granted		1,259,150			29.05
Options exercised		(757,573	)		11.42
Options canceled		(142,391	)		33.90
Balance at June 30, 2017		6,176,302		$	27.53

Summary of PSO Activity

The following table summarizes PSO activity under our 2013 Plan and related information during the six months ended June 30, 2017:

	Shares
	Subject to		Weighted-
	Outstanding		Average Exercise
	Options		Price Per Share
Balance at December 31, 2016		180,752	$	23.76
Options granted		—		—
Options exercised		—		—
Options canceled		—		—
Balance at June 30, 2017		180,752	$	23.76

Summary of RSU Activity

The following table summarizes RSU activity, under our 2013 Plan and related information:

	Shares
	Subject to			Weighted-
	Outstanding			Average grant date
	RSUs			fair value per share
Balance at December 31, 2016		546,507		$	28.38
RSUs granted		335,050			26.41
RSUs released		(211,882	)		28.26
RSUs canceled		(23,022	)		27.42
Balance at June 30, 2017		646,653		$	27.43

Summary of PSU Activity

The following table summarizes PSU activity, under our 2013 Plan and related information:

	Shares
	Subject to			Weighted-
	Outstanding			Average grant date
	PSUs			fair value per share
Balance at December 31, 2016		285,866		$	29.24
PSUs granted		143,750			25.54
PSUs released		(8,917	)		50.30
PSUs canceled		(52,281	)		33.76
Balance at June 30, 2017		368,418		$	26.64

Classification of Stock-Based Compensation Expense

The table below sets forth the functional classification of stock-based compensation expense, net of estimated forfeitures, for the periods presented (in thousands):

	Three Months Ended June 30,				Six Months Ended June 30,
	2017		2016		2017		2016
Research and development	$	6,670	$	3,066	$	10,820	$	6,096
Selling, general and administrative		6,587		4,556		11,471		8,595
Total stock-based compensation	$	13,257	$	7,622	$	22,291	$	14,691